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Amaehealth

Product Operations Manager

San Francisco, CA

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Role family
Operations
Seniority
Lead / management
Country
US
Work mode
On-site / unstated
First seen by hirly
3 Sept 2026

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the posting

The Problem

Severe mental illness affects over 15 million adults in the United States. Schizophrenia. Schizoaffective disorder. Bipolar I. Treatment-resistant depression. These are the conditions the rest of healthcare has systematically failed to build for.

What makes this problem different from most of healthcare is that the tools to solve it do not exist. The clinical protocols, the measurement science, the precision medicine, the technology to deliver coordinated longitudinal outpatient care for this population. None of it has been built. This is a frontier problem, and it requires frontier science and care delivery to solve.

We are developing all of it. The care, the science, the technology.

Product Operations Manager

San Francisco, CA (In-person)

The Problem

Severe mental illness affects over 15 million adults in the United States. Schizophrenia. Schizoaffective disorder. Bipolar I. Treatment-resistant depression. These are the conditions the rest of healthcare has systematically failed to build for.

What makes this problem different from most of healthcare is that the tools to solve it do not exist. The clinical protocols, the measurement science, the precision medicine, the technology to deliver coordinated longitudinal outpatient care for this population. None of it has been built. This is a frontier problem, and it requires frontier science and care delivery to solve.

We are developing all of it. The care, the science, the technology.

Who We Are

Amae Health is a Series B, venture-backed Public Benefit Corporation delivering specialty outpatient care for people with severe mental illness through high-acuity, in-person clinics nationwide.

Our integrated model brings psychiatry, therapy, primary care, dietitians, and community support together under one roof. Leading health systems—including NewYork-Presbyterian, Cedars-Sinai, Mass General Brigham, Novant Health, and CommonSpirit—collaborate with us to expand this level of care.

Alongside care delivery, we are building the science and technology the field has long lacked—proprietary clinical protocols, novel measurement, and an AI-driven data platform designed for severe mental illness.

The impact: fewer hospitalizations, greater stability, and more people living meaningful lives in their communities.

The Team

We are clinicians, operators, technologists, and scientists who chose Amae because the problem is hard and the stakes are real. We are not interested in incremental improvements to a broken system

Our teams work cross-functionally because the work demands it. The psychiatrist informs the product roadmap. Engineers understand the clinical complexity their technology must solve. Researchers sit alongside the operators running the clinics their work measures.

Every function—finance, product, people, growth, technology—exists to serve one goal: better outcomes for the people we care for.

The Role

Product is core to how we scale mental health care and how we get better outcomes for patients.

As our Product Operations Manager, you'll own how the product actually gets delivered, adopted, and improved in the real world. You'll sit at the center of Product, Engineering, and Clinical teams, turning strategy into execution, and execution into outcomes.

This is a high-ownership, high-ambiguity role. You won't just support the system, you'll build it.

What You'll Do

Launch & Clinical Enablement

Drive product launches from initial rollout planning through go-live.

Build and maintain scalable launch playbooks that ensure new features and capabilities land seamlessly and effectively across all clinic environments.

Translate product into practice; design training, materials, and workflows that clinicians actually use, and run live sessions to build team confidence with new tools

Give clinic ops a rolling quarter of visibility, so training capacity is planned rather than scrambled, and batch related releases into single training moments

Own release notes end to end: plain language for a busy provider between visits, with a "why this matters" line on every entry

Own documentation standards - structure, ownership, review cadence

Roadmap & Operating Cadence

Drive coordination across Product, Engineering, and Clinical teams to bring structure to ambiguity.

Maintain high-level momentum by tracking dependencies and removing cross-team blockers to push initiatives across the finish line

Maintain the central roadmap and establish the operational cadence (e.g., quarterly planning) to ensure a unified view of ongoing engineering work, timelines, and goals.

Design and run the processes that structure stakeholder feedback and reprioritization, empowering Product Leadership to make informed strategic decisions.

Manage the intake of support tickets and product feedback, translating real-world insights into actionable inputs.

Run the release tracker to monitor target windows, desired clinical or member outcomes, affected roles, and post-launch adoption signals.

Analytics & Outcome Measurement

Monitor and report on product KPIs, both at the product level and on a launch-by-launch basis

Track outcomes, not just adoption; success is measured by improvement on the dimension a launch was meant to move, not just uptake

Maintain dashboards and a reporting cadence that give Product and leadership visibility into clinical and product performance

Do What It Takes

We're a startup—no job is too small

You'll step in wherever needed to move the work forward

What We're Looking For

5+ years in Product Operations, GTM, Business Operations or similar execution-heavy roles

Tech-focused healthcare startup experience required—ideally with direct exposure to providers/clinicians and the pressures and tools they work with

Proven track record of launching products and driving adoption

Track record of measuring adoption and outcomes post-launch, as well as ongoing product KPIs

Strong analytical instincts; comfortable defining metrics, working with product analytics/data, building and maintaining dashboards and reports that teams trust

Experience writing for non-technical operational audiences; release notes, documentation, enablement material

Strong systems thinker; you've built processes that scale across teams

Exceptional communicator; you can translate between engineers, clinicians, and operators

Experience managing feedback loops, support workflows, or ticket triage

Comfortable operating in ambiguity; you create clarity where none exists

High urgency and ownership; you move fast and finish what you start

Fluency with AI tools (especially Claude) to increase speed and leverage

Deep alignment with our mission to improve mental health care

Able to work in-person from our San Francisco HQ with frequent travel to our clinics in San Mateo and Los Altos

Why This Role Matters

Every product we ship directly impacts patient care.

If we get this right:

Clinicians work more effectively

Patients receive better care

We scale faster without breaking

You're not just improving a product, you're helping build a system that changes lives.

What We’re Building

Most healthcare companies ask you to optimize an existing system. We’re building one that has never existed.

A national care model designed for the highest-acuity patients in behavioral health.

Precision medicine for severe mental illness, using multimodal clinical, behavioral, and social data to personalize treatment.

A clinical operating system that integrates longitudinal data, real-time patient signals, and purpose-built tools into a single decision layer.

New science and measurement frameworks to define what real outcomes look like in SMI—stability, functional improvement, and hospitalizations avoided.

A health-system partnership model proving coordinated SMI care can work at scale.

If you want to maintain the status quo, this isn’t the

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Product Operations Manager at Amaehealth — hirly