Amaehealth
Product Operations Manager
San Francisco, CA
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hirly's read of this role
- Role family
- Operations
- Seniority
- Lead / management
- Country
- US
- Work mode
- On-site / unstated
- First seen by hirly
- 3 Sept 2026
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the posting
The Problem
Severe mental illness affects over 15 million adults in the United States. Schizophrenia. Schizoaffective disorder. Bipolar I. Treatment-resistant depression. These are the conditions the rest of healthcare has systematically failed to build for.
What makes this problem different from most of healthcare is that the tools to solve it do not exist. The clinical protocols, the measurement science, the precision medicine, the technology to deliver coordinated longitudinal outpatient care for this population. None of it has been built. This is a frontier problem, and it requires frontier science and care delivery to solve.
We are developing all of it. The care, the science, the technology.
Product Operations Manager
San Francisco, CA (In-person)
The Problem
Severe mental illness affects over 15 million adults in the United States. Schizophrenia. Schizoaffective disorder. Bipolar I. Treatment-resistant depression. These are the conditions the rest of healthcare has systematically failed to build for.
What makes this problem different from most of healthcare is that the tools to solve it do not exist. The clinical protocols, the measurement science, the precision medicine, the technology to deliver coordinated longitudinal outpatient care for this population. None of it has been built. This is a frontier problem, and it requires frontier science and care delivery to solve.
We are developing all of it. The care, the science, the technology.
Who We Are
Amae Health is a Series B, venture-backed Public Benefit Corporation delivering specialty outpatient care for people with severe mental illness through high-acuity, in-person clinics nationwide.
Our integrated model brings psychiatry, therapy, primary care, dietitians, and community support together under one roof. Leading health systems—including NewYork-Presbyterian, Cedars-Sinai, Mass General Brigham, Novant Health, and CommonSpirit—collaborate with us to expand this level of care.
Alongside care delivery, we are building the science and technology the field has long lacked—proprietary clinical protocols, novel measurement, and an AI-driven data platform designed for severe mental illness.
The impact: fewer hospitalizations, greater stability, and more people living meaningful lives in their communities.
The Team
We are clinicians, operators, technologists, and scientists who chose Amae because the problem is hard and the stakes are real. We are not interested in incremental improvements to a broken system
Our teams work cross-functionally because the work demands it. The psychiatrist informs the product roadmap. Engineers understand the clinical complexity their technology must solve. Researchers sit alongside the operators running the clinics their work measures.
Every function—finance, product, people, growth, technology—exists to serve one goal: better outcomes for the people we care for.
The Role
Product is core to how we scale mental health care and how we get better outcomes for patients.
As our Product Operations Manager, you'll own how the product actually gets delivered, adopted, and improved in the real world. You'll sit at the center of Product, Engineering, and Clinical teams, turning strategy into execution, and execution into outcomes.
This is a high-ownership, high-ambiguity role. You won't just support the system, you'll build it.
What You'll Do
Launch & Clinical Enablement
Drive product launches from initial rollout planning through go-live.
Build and maintain scalable launch playbooks that ensure new features and capabilities land seamlessly and effectively across all clinic environments.
Translate product into practice; design training, materials, and workflows that clinicians actually use, and run live sessions to build team confidence with new tools
Give clinic ops a rolling quarter of visibility, so training capacity is planned rather than scrambled, and batch related releases into single training moments
Own release notes end to end: plain language for a busy provider between visits, with a "why this matters" line on every entry
Own documentation standards - structure, ownership, review cadence
Roadmap & Operating Cadence
Drive coordination across Product, Engineering, and Clinical teams to bring structure to ambiguity.
Maintain high-level momentum by tracking dependencies and removing cross-team blockers to push initiatives across the finish line
Maintain the central roadmap and establish the operational cadence (e.g., quarterly planning) to ensure a unified view of ongoing engineering work, timelines, and goals.
Design and run the processes that structure stakeholder feedback and reprioritization, empowering Product Leadership to make informed strategic decisions.
Manage the intake of support tickets and product feedback, translating real-world insights into actionable inputs.
Run the release tracker to monitor target windows, desired clinical or member outcomes, affected roles, and post-launch adoption signals.
Analytics & Outcome Measurement
Monitor and report on product KPIs, both at the product level and on a launch-by-launch basis
Track outcomes, not just adoption; success is measured by improvement on the dimension a launch was meant to move, not just uptake
Maintain dashboards and a reporting cadence that give Product and leadership visibility into clinical and product performance
Do What It Takes
We're a startup—no job is too small
You'll step in wherever needed to move the work forward
What We're Looking For
5+ years in Product Operations, GTM, Business Operations or similar execution-heavy roles
Tech-focused healthcare startup experience required—ideally with direct exposure to providers/clinicians and the pressures and tools they work with
Proven track record of launching products and driving adoption
Track record of measuring adoption and outcomes post-launch, as well as ongoing product KPIs
Strong analytical instincts; comfortable defining metrics, working with product analytics/data, building and maintaining dashboards and reports that teams trust
Experience writing for non-technical operational audiences; release notes, documentation, enablement material
Strong systems thinker; you've built processes that scale across teams
Exceptional communicator; you can translate between engineers, clinicians, and operators
Experience managing feedback loops, support workflows, or ticket triage
Comfortable operating in ambiguity; you create clarity where none exists
High urgency and ownership; you move fast and finish what you start
Fluency with AI tools (especially Claude) to increase speed and leverage
Deep alignment with our mission to improve mental health care
Able to work in-person from our San Francisco HQ with frequent travel to our clinics in San Mateo and Los Altos
Why This Role Matters
Every product we ship directly impacts patient care.
If we get this right:
Clinicians work more effectively
Patients receive better care
We scale faster without breaking
You're not just improving a product, you're helping build a system that changes lives.
What We’re Building
Most healthcare companies ask you to optimize an existing system. We’re building one that has never existed.
A national care model designed for the highest-acuity patients in behavioral health.
Precision medicine for severe mental illness, using multimodal clinical, behavioral, and social data to personalize treatment.
A clinical operating system that integrates longitudinal data, real-time patient signals, and purpose-built tools into a single decision layer.
New science and measurement frameworks to define what real outcomes look like in SMI—stability, functional improvement, and hospitalizations avoided.
A health-system partnership model proving coordinated SMI care can work at scale.
If you want to maintain the status quo, this isn’t the
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