Senior Clinical Trial Manager (Sr. CTM) 5948-204

Senior Clinical Trial Manager (Sr CTM) NX-5948-204

You’ve run trials well — now run more of them, and help others do the same. You’ll manage a portfolio of trials or a full region, own vendor strategy end-to-end, and become the person other CTMs turn to when something’s stuck.

Position Description

This individual manages clinical regions and/or multiple trials simultaneously, with broad involvement in work central to Nurix’s strategic goals, and plays a key role in developing junior clinical operations staff.

The Opportunity

Own operational strategy across multiple clinical trials and/or a full geographic region

Shape protocol strategy and provide senior input on study design and data collection approach

Lead vendor/CRO selection strategy and own contract negotiation leverage across trials

Serve as the escalation point for vendor or site issues CTMs can’t resolve on their own

Own program-level budget forecasting and proactively flag financial risk across the portfolio

Mentor and develop CTMs and CTAs, providing hands-on guidance and informal supervision

Lead audit readiness strategy and serve as the point person across multiple trials during inspections

Represent Clinical Operations at the program or franchise level, and represent Nurix externally at professional events

Anticipate risk across the trial portfolio and shape process or strategy to prevent issues before they surface

Lead cross-functional strategic initiatives rather than simply participating in them

What You’ll Bring

S./B.A. in biological sciences with 8-10+ years of relevant industry experience

Ability to travel as required for the program (25%)

Deep working knowledge of FDA, EMA, ICH, and GCP regulations and guidelines

Proven experience managing global trials or multi-region programs

Track record leading vendor/CRO relationships at a strategic, not just operational, level

Experience mentoring or developing junior CTMs/CTAs

Strong executive presence and ability to influence without direct authority

Comfortable operating with minimal oversight and setting direction for others

Outstanding organizational skills, able to manage a portfolio of trials simultaneously

Thrives in a fast-paced, small-company environment, adjusting priorities as needed

Salary Range: $181,900 – $193.827 annually

The posted range applies to roles based in the San Francisco Bay Area and reflects local market conditions. Where an offer lands within that range depends on the candidate’s relevant experience, technical expertise, and how their background aligns with the role’s requirements.

Location: Onsite – Brisbane, CA

Fit with Nurix Culture and Values

Strong team orientation; highly collaborative

Solutions and results-oriented focus

Hands-on approach; resourceful and open to diverse points of view

About Nurix Therapeutics

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.