hirly

Alumis

Senior Manager, People & Culture Operations

South San Francisco

Apply through hirly

hirly scores this role against your resume, shows its reasoning, then writes a resume and cover letter for it and fills the application with you. Free to start — no card required.

hirly's read of this role

Seniority
Lead / management
Stated salary
$156,900 per year
Work mode
On-site / unstated
First seen by hirly
3 Sept 2026

Derived automatically from the posting. Sign up to see how the role scores against your own resume.

the posting

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients.

The Senior Manager, People & Culture Operations, will report to the Senior Director, People & Culture, to establish and maintain strong HR operational framework. This position will manage the day-to-day input of the HRIS, offer process, onboarding and offboarding, as well as all operational excellence related to annual merit process, employee reward and recognition programs.

Responsibilities

Offer and Onboarding Process including New Hire Orientation

Exit and Offboarding Process

Daily maintenance of Alumis’ HRIS, supporting system enhancements, and ensuring efficient HR operations.

Management of the employee reward and recognition programs and processes

Administer mandatory employee training by tracking completion, maintaining records, issuing reminders, and ensuring compliance with federal, state, and company requirements.

Manage and maintain employee swag inventory, fulfillment processes, and vendor coordination

Identify opportunities for process improvements and automation to increase efficiency and scalability

Process verifications of employment

Maintain P&C SharePoint site

Strong partnership with Total Rewards, HR Business Partners and Talent Acquisition teams

Adhoc P&C team administrative support

Must Have Skills/Experience

Bachelor’s Degree in related field.

7+ years’ experience in HR, HR operations, customer services

Strong business and HR acumen.

High level of discretion and ability to handle sensitive and confidential information.

Exceptional attention to detail.

Ability to manage multiple priorities and meet deadlines in a fast-paced environment.

Ability to consistently meet or exceed goals and KPIs with excellence mind-set.

Knowledge of large-scale data management, payroll, time and HRIS systems solutions and strong skills in technologies.

Understanding of interactions between HR, accounting, and finance.

Demonstrated ability to influence across teams and collaborate well with cross-functional partners.

Strong analytical, problem-solving, planning, decision-making skills and process orientation.

Experience in continuous improvement projects.

Proficient in Microsoft Office applications, including Excel, Word, PowerPoint, and Outlook, as well as SharePoint

Nice-to-Have Skills/Experience

Current/Previous HRIS experience (BambooHR)

HR Policy experience

Strong process and project management skills

Ability to work within the gray

Strong communication skills

This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday.

The salary range for this position is $156,900 USD to $185,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.

Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.

Other benefits include:

Health insurance premiums paid at 90% for employee, 80% for dependents

Free access to Genentech Bus & Ferry Share program

$100 monthly cell phone stipend

Unlimited PTO for Exempt employees

Free onsite gym and a kitchen stocked with yummy snacks and drinks!

We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate , challenge and nurture one another along the way.

Alumis Inc. is an equal opportunity employer.

Browse similar roles

Is this role actually a fit for you?

hirly answers with a score and its reasoning, then writes the resume and cover letter if you decide to go for it.

Score it against my resume
Senior Manager, People & Culture Operations at Alumis — hirly