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Definiumtherapeutics

Staff Accountant

Remote

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Role family
Finance
Seniority
Lead / management
Stated salary
$75,000 per year
Work mode
Remote-friendly
First seen by hirly
22 Sept 2026

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the posting

Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.

Our lead product candidate, lysergide tartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.

Guided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.

Together we are moving psychiatry forward—beyond better, into a boundless future. Join us!

Reporting to the Senior Manager, Accounting, the Staff Accountant will play a key role in our accounting team, with a strong emphasis on accounts payable and general ledger accounting. This role will be responsible for processing invoices and weekly payments, preparing journal entries and working closely with other team members in a fast-paced, public company environment.

Responsibilities

Process and review vendor invoices through Coupa, ensuring appropriate coding, supporting documentation, and approvals are obtained

Assist with vendor setup and maintenance as needed

Research and resolve invoice discrepancies and vendor inquiries.

Maintain accurate and complete AP records and supporting documentation

Assist with month-end AP close activities, including reviewing outstanding invoices and accrued expenses

Prepare and process weekly vendor payments through Coupa in accordance with established payment procedures and internal controls

Assist with cash activity and bank-related accounting, including recording miscellaneous cash receipts and disbursements

Prepare miscellaneous and routine general ledger journal entries with appropriate supporting documentation

Assist with bank and cash account reconciliations and investigate reconciling items

Support month-end and quarter-end close activities

Perform other accounting, compliance, and internal control-related responsibilities as needed to support the company’s financial reporting and growth objectives

Qualifications

Bachelor’s degree in Accounting, Finance, or related field

Previous experience with Coupa preferred

Previous experience with NetSuite preferred

1-3+ years of accounting experience within the life science industry preferred

Previous experience with accounting in a publicly traded company required

Familiarity with SOX and internal control requirements

Excellent written and verbal communication skills, along with the ability to present numeric data effectively

Exceptional time-management abilities and strong follow-through skills required

Experience thriving in a fast-paced environment, managing competing priorities with minimal supervision

Professional, team-oriented, collaborative, and “can-do” attitude

Intermediate-to-advanced MS Office skills (Outlook, Word, Excel, PowerPoint)

Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.

Employees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including:

100% paid health benefits including Medical, Dental and Vision for you and your dependents

401(k) program with company match and vesting after the turn of the first month after your start date

Flexible time off

Generous parental leave and some fun fringe perks!

The starting base pay range for this position:

$75,000 — $90,000 USD

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