Senior Director, PMO and COE

Use Your Power for Purpose

The Senior Director, ES Program Management and Center of Excellence serves, as a pivotal strategic leader within External Supply (ES), responsible for shaping and supporting the future of ES strategy, intelligence, governance, and execution across the organization.

The role provides strategic leadership, deployment and value realization for the teams and capabilities responsible for advancing ES Vision and Strategy, EMAP Operating Efficiencies, Program Management and Center of Excellence. The incumbent provides executive oversight of the ES strategic portfolio and PC1 technology transfer program portfolio, ensuring strategic initiatives remain aligned with enterprise objectives and deliver measurable business outcomes. Success is achieved through influence rather than authority, bringing together diverse stakeholders, aligning competing priorities, and converting strategy into value. The ideal candidate is a visionary strategist, exceptional collaborator, and transformational leader with a passion for building capabilities, enabling informed decisions, and helping shape the future of External Supply. The incumbent leads a global organization of 10 direct reports (5 Directors and 5 Managers) across the Center of Excellence team (Ireland Hub and Tampa, FL Hub), and is accountable for ensuring effective support to all ES Clusters and Categories through the delivery of governance, operational support, digital transformation, performance management, and continuous improvement initiatives. The role regularly engages and influences stakeholders across the entire ES community, spanning from Operations colleagues through VP and Senior Vice President levels, and requires managing highly complex program management across this full breadth of the organization. The incumbent carries executive accountability for the ES EMAP Operating Efficiencies program, targeting a 6% cost reduction across total ES vendor spend, currently estimated at $414M over a 3-year horizon. The PC1 technology transfer portfolio further requires the incumbent to navigate a complex external stakeholder network spanning internal Pfizer Site leaders, Client Senior Leaders (up to and including CEO-level executives), and PGS/ES senior leadership, with a revenue of $1.02B to Pfizer Inc.

Incumbent to lead in AI-native culture building and AI efficient/effective business processes establishments across Program Management Office and Center of Excellence.

What You Will Achieve

Program Management Office & Strategic Portfolio Execution

Strategic Portfolio Oversight

Provide executive oversight for the ES strategic portfolio, ensuring initiatives remain aligned to enterprise priorities and leadership objectives.

Establish governance and prioritization frameworks that enable informed resource allocation, sequencing initiatives, management of dependencies, and visibility to strategic tradeoffs.

Ensure leadership maintains an integrated view of portfolio performance, risk, value realization, and organizational capacity.

Lead ES Vision and Strategy Deployment and Value Realization Program

Lead ES EMAP Operating Efficiencies Polaris multi-year Savings Program, targeting a 6% cost reduction across total ES vendor spend (currently estimated at $414M over 3 years)

Program Excellence & PMO Capability Leadership

Provide leadership oversight for the ES Program Management Office and the team responsible for execution of strategic initiatives.

Establish program management standards, governance processes, methodologies, and reporting expectations that drive consistency and execution excellence across the portfolio.

Ensure program risks, dependencies, issues, and value realization are effectively managed, escalated, and communicated.

PC1 Technology Transfer Program Oversight

Provide executive oversight and governance for the PC1 technology transfer program portfolio, ensuring alignment with commercial objectives, strategic priorities, and network plans.

Lead the team responsible for program management, reporting, risk management, stakeholder coordination, and portfolio visibility across PC1 transfer initiatives.

Ensure leadership has clear visibility to transfer performance, critical milestones, resource requirements, financial implications, and escalation needs.

Partner with internal Pfizer Site leaders, Client Senior Leaders (including CEO-level executives), and PGS/ES senior leadership to address barriers and maintain delivery commitments across the full external stakeholder network.

COE Leadership & People Management

Lead, coach, and develop the CoE Team to ensure delivery of strategic and operational priorities across the ES network.

Establish clear priorities, objectives, and performance expectations for the CoE team.

Build organizational capability in Continuous Improvement, Digital Transformation, AI adoption, and Process Excellence.

Foster a culture of collaboration, accountability, innovation, and continuous improvement.

Manage resource allocation and workforce planning to ensure effective support across assigned ES Categories and Clusters.

Designing and implementing new business processes where required.

Coach COE team in the Following

Direct and coach the CoE team's facilitation of Category governance, including IMEx forums, VSLT operating reviews, and CRM/BRM processes, ensuring stakeholder alignment, consistent communication cadence, and support for Category strategy development across all ES Categories and Clusters.

Set the standard for performance visibility and continuous improvement, directing the CoE's development of dashboards, metrics, and business reviews while coaching the team in structured problem-solving to drive operational effectiveness and execution excellence across the network.

Serve as the senior Operational Excellence authority for the organization, coaching the CoE team in OE methodologies, leading capability-building programs, and directing knowledge management and best-practice deployment across Categories and Clusters.

Direct the CoE's delivery of operational support to ES Categories and Clusters, including VSOT governance, category issue resolution, supplier/sample-shipment coordination, and T4 Continuous Improvement Loop activities, ensuring consistent, high-quality execution across the network.

Champion AI fluency and digital transformation, coaching the CoE team on deployment, adoption, and troubleshooting of digital tools, while directing organizational change management, audit readiness, and compliance governance across the ES network.

Sustainment & Business Process Ownership

Ensure the long-term sustainability of improvements and business processes by:

Leading project transitions into Business-As-Usual (BAU).

Establishing process ownership, governance, and accountability models.

Embedding best practices across the organization.

Supporting integration of newly implemented processes into Category operations.

Monitoring performance and ensuring benefits realization from improvement initiatives.

Additional Duties: Perform other responsibilities as assigned to meet business and operational needs

Here Is What You Need (Minimum Requirements)

Applicant must have a bachelor's degree with at least 12 years of experience; OR a master's degree with at least 10 years of experience; OR a PhD with 7+ years of experience.

Progressive leadership experience in strategy, program management, supply chain, network strategy, operational excellence, pharmaceutical manufacturing, business development, or related disciplines.

Demonstrated experience leading complex, cross-functional initiatives and influencing executive-level decision-making within a matrixed global organization.

Experience translating strategic priorities into executable plans and delivering measurable business outcomes through effective governance and stakeholder alignment.

Experience sup