AION Biosciences
Computational MRI Physicist
St. Louis
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hirly's read of this role
- Seniority
- Mid level
- Country
- US
- Work mode
- On-site / unstated
- First seen by hirly
- 28 Sept 2026
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the posting
At AION, we’re building sci-fi medical devices.
Our mission is to bring aging under full biomedical control. We believe this can be achieved through closed-loop hardware that reads and writes biological states in living tissue using electromagnetic and acoustic fields.
We're looking for exceptional scientists and engineers to join us in building machines that make aging optional.
The Role
As a Computational MRI Physicist at AION, you will:
Build the computational layer that turns raw MR signals into quantitative measurements of tissue state
Develop physics-based models and simulation tools for our low-field, single-sided MRI systems
Develop reconstruction and parameter-estimation methods for T1, T2, diffusion, proton density, and other quantitative tissue properties
Design acquisition strategies that maximize biological information per unit of time
Build methods for uncertainty estimation, calibration, and longitudinal measurement
Work directly with MRI engineers and biologists across simulation, hardware, and biological experiments
Advance quantitative MRI, MR fingerprinting, field-cycling relaxometry, and model-based reconstruction
You
We value mission alignment, integrity, and ambition over pedigree.
Strong first-principles thinker across physics, mathematics, software, and hardware
Deep intuition for MRI physics, inverse problems, and quantitative measurement
Strong scientific computing, signal processing, and numerical optimization ability
Experience with quantitative MRI, reconstruction, computational imaging, or related fields
Comfortable moving quickly between theory, simulation, and experimental systems
Exceptional technical ownership and willingness to work on hard, unsolved problems
Details
St. Louis, MO (on-site).
Equity for the right person.
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