Axsome Therapeutics
Manager, Accounting
New York, NY
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- Seniority
- Lead / management
- Country
- US
- Work mode
- Remote-friendly
- First seen by hirly
- 10 Sept 2026
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the posting
Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, agitation associated with dementia due to Alzheimer’s disease, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, as well as multiple novel product candidates addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X .
About This Role
Axsome Therapeutics is seeking an Accounting Manager to help lead the Company's accounting operations, financial reporting, and close processes. This role will partner with stakeholders across the organization to ensure accurate, financial reporting, strengthen internal controls, and drive process improvements that support the Company's growth. This position reports to the Assistant Controller.
This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.
Job Responsibilities and Duties include, but are not limited to, the following:
Plan, direct, and coordinate all accounting functions
Review existing processes and functions for automation, enhancements, and improvements, including ERP, Procure to Pay, and Order to Cash process/systems
Manage the monthly and quarterly close process and the consolidation of all financial data necessary for an accurate financial statement results and reporting
Assist with the processes for budgets and forecasting, and preparation of variance analysis of budgets/forecast to actuals
Support the financial reporting process for all SEC filings (10-Q, 10-K, Proxy) as well as review of external communications, including press releases, earnings releases, prepared remarks, and corporate deck
Research, document, and provide support for accounting positions and technical accounting memos under US GAAP
Coordinate quarterly reviews and annual audits with external auditors
Assist and coordinate tax compliance tasks with external tax accountants, including providing required information for periodic tax reporting, and annual tax returns for federal, state, and local governments, international countries, and reviewing supporting tax schedules and filings
Participate in the preparation and documentation of SOX narratives, development of control evidence expectations, detailed SOX testing plans and reviewing test guidance/scripts for completeness and accuracy
Support with planning, facilitate, and provide guidance with management’s execution and verification that the SOX assessment of internal controls over financial reporting is performed in accordance with the Company’s control assessment approach
Manage equity plan administration, including Black Scholes fair market value calculations with third party vendor, issuance of new grants, exercises, cancellations, and forfeitures and work with third party vendor to process grants in online equity system
Provide management with financial information to support decision-making process, including ad hoc reporting and management reports
Provide leadership and the ability to influence key decisions, both as it pertains to the overall business needs and to the Accounting/Finance function
Requirements / Qualifications
Bachelor’s degree in accounting/finance
Certified Public Accountant
6+ years of progressive accounting experience in the biotech industry or Big 4 accounting firms
Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles
Experience, Knowledge and Skills
Excellent interpersonal, verbal, and written communication skills
Comfortable multi-tasking in a fast-paced environment with minimal direction and able to adjust workload based upon changing priorities
Excellent team player: willingness to work/collaborate in a growing organization
Strong understanding of accounting systems and GAAP / SEC reporting requirements
Strategic/analytical thinker, with strong influencing skills able to partner
Proficient in MS Office and accounting systems such as MS Dynamics
Salary and Benefits:
The anticipated salary range for this role is $90,000 - $120,000. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.
Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.
Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.
Listed on hirly, a job board. hirly is not the employer: Axsome Therapeutics is hiring for this role.
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