Thermo Fisher
Operational Excellence - Sr. Manager
St. Louis, Missouri, USA
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hirly's read of this role
- Seniority
- Lead / management
- Country
- US
- Work mode
- On-site / unstated
- First seen by hirly
- 24 Sept 2026
Derived automatically from the posting. Upload your resume above to see how the role scores against it.
the posting
Work Schedule
Standard (Mon-Fri)
Environmental Conditions
Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Office
Job Description
Move fast. Think big. Make an impact that can change lives.
At Thermo Fisher Scientific’s St. Louis site, we move with urgency because what we do matters. Every day, our teams are helping turn breakthrough science into biologic medicines for patients around the world—and behind every batch, every decision and every challenge we solve is a patient waiting for what we make.
This is a fast-paced, high-energy environment where science, technology and talented people come together to do extraordinary work. Whether you’re in manufacturing, quality, engineering, the lab or a support function, you are part of the mission. Your expertise matters. Your ideas matter. Your ability to move quickly, solve problems and deliver matters.
DESCRIPTION
As a Senior Manager of PPI Business System at Thermo Fisher Scientific, you will facilitate transformational change and continuous improvement across the organization. Leading the implementation of our Practical Process Improvement (PPI) Business System, you will partner with business leaders to establish and mature lean management practices that enable profitable growth, enhance customer experience, and increase employee engagement. Through strategic deployment, coaching, and hands-on facilitation of improvement initiatives, you will help develop a problem-solving culture focused on operational excellence. You'll collaborate with cross-functional teams to streamline processes, eliminate waste, and deliver measurable results in quality, productivity, and customer satisfaction.
As a strategic partner, coach, and hands-on improvement leader, you will help build a culture of continuous improvement and structured problem solving. You will work across functions and organizational levels to identify improvement opportunities, facilitate high-impact initiatives, develop organizational capability, and ensure improvements deliver measurable and sustainable business results.
REQUIREMENTS
Advanced Degree plus 6 years of experience, or Bachelor's Degree plus 8 years of experience in lean leadership implementing continuous improvement initiatives
Hands on experience in operational excellence, lean, continuous improvement, or PPI in a complex operational or manufacturing environment.
Lean Six Sigma Black Belt required
Project Management Professional (PMP) certification a plus
- Demonstrated experience developing and deploying PPI/lean tools including:
- Strategy deployment and value stream mapping
- Tiered daily management systems and leader standard work
- Kaizen facilitation and problem-solving methodologies
- Standard work, error-proofing, and visual management
- Strong financial and business acumen with ability to identify, quantify and track improvement opportunities
Excellent communication, presentation and influence skills to engage all organizational levels
Demonstrated success coaching and developing continuous improvement capabilities in others
Experience leading change initiatives in a matrix organization
Strong project management skills and ability to manage multiple priorities
Ability to travel up to 20%
Manufacturing/operations experience preferred
Expertise in data analytics and performance metrics
Proficiency in Microsoft Office suite required
Commitment to driving improvement and leading transformational change
Ability to work effectively across functions without direct authority
Experience in regulated industry (e.g., life sciences, medical devices) preferred
Compensation & Benefits
We offer competitive compensation and a comprehensive Total Rewards package designed to support your health, wellbeing, financial security and life outside of work. Benefits include medical, dental and vision coverage, retirement and savings programs, paid time off, wellbeing resources, business resource groups, career development opportunities and additional programs to support you and your family.
Compensation will be determined based on factors including experience, skills, education, internal equity, geographic location and other job-related considerations.
Because when you’re helping us deliver for patients, we want to help you thrive—at work and beyond.
Other
Relocation assistance is not provided.
Must be legally authorized to work in the United States now and in the future, without sponsorship.
Must be able to pass a comprehensive background check, which includes a drug screening.
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