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Valthos

Operations - Generalist / Business Operations

New York

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hirly's read of this role

Role family
Operations
Seniority
Mid level
Country
US
Work mode
On-site / unstated
First seen by hirly
2 Sept 2026

Derived automatically from the posting. Upload your resume above to see how the role scores against it.

the posting

Generalist / Business Operations

Valthos Inc.

Valthos is an applied biological intelligence company. We build and deploy software and biological AI systems to safeguard humanity.

The same AI architectures that enable self-driving cars, land rockets with precision, and deliver expert-level reasoning are beginning to be deployed in biological design. To stay ahead, we must advance our arsenal of tools to capture and design against real-time sensitivities in nature's evolving mutational landscape.

We are a group of mission-driven software engineers from Palantir and applied biological ML engineers from MIT's Broad Institute and DeepMind making the latest advances in computational biology accessible in the real-world for federal and commercial use.

Operations at Valthos is the function that keeps the company moving. It covers the full range: keeping the office running, closing fundraising rounds, talking to customers, and building out the operational infrastructure underneath it all. It is a generalist role by design.

On any given day, you might be troubleshooting a broken A/C unit before lunch, building a financial model for the board deck after, and project-managing a vendor onboarding by the end of the day. We are a small team working on problems that matter. We need someone who will pick up whatever needs picking up, execute well, and do the work no one else wants to do, while also being trusted with some of the most sensitive and strategic decisions the company makes.

You will work directly alongside the head of operations and founders on the highest-leverage problems we face. You will own projects end-to-end, from definition, to solutioning, to implementation, across every function: finance, recruiting, people, legal, facilities, IT, and whatever else comes up. Early on, you will hold many hats simultaneously. Over time, as we grow, the hats you choose to keep will define your role and likely seed an entire function at Valthos.

Whether you aspire to be an entrepreneur, a future operator, or to build a category-defining company's operating spine, we believe Valthos is the best place, with the best colleagues, to learn how. You will learn how to unpack a problem, understand the costs and consequences of its solution, and ship. You will make decisions independently, alongside a small team that will support and challenge you as you grow.

The Role

Own the company's day-to-day operations: facilities, IT, office management, vendor management, travel, and anything else required to keep the team productive

Build the financial backbone of the company: construct and maintain financial models, scenario-plan budget and runway, partner with external accounting on close, and run spend, payroll, and treasury as needed

Stand up core business infrastructure, including equity administration, benefits, payroll, corporate policies, compliance, and vendor systems, choosing tools pragmatically and replacing them when we outgrow them

Support recruiting and people operations end-to-end: source candidates, run scheduling, manage offers and onboarding, and help architect the culture and operating cadence of the company

Lead special projects that do not fit neatly into anyone else's job description, from standing up security and clearance workflows, to opening a new office, to running internal offsites and all-hands

Provide operational support to commercial and government engagements as needed, helping the team move proposals, contracts, and procurement workflows across the finish line

Serve as the operational face of Valthos with external partners (investors, regulators, contractors, and vendors), and represent the company with the same bar of care as a founder would

Close the feedback loop between the team and our partners: translate what you learn from investors, customers, and vendors into the decisions and priorities that shape how we run

Qualifications (required)

3+ years in a high-ownership, high-tempo operational role, such as early-stage startup operator, chief of staff, investment banking, management consulting, private equity, or venture capital

Demonstrated ability to own projects end-to-end in ambiguous environments, with minimal structure and minimal supervision

Strong financial and analytical fluency; comfortable building models in Excel, running scenario analyses, and reasoning from numbers under time pressure

Exceptional written and verbal communication. You will draft memos, investor updates, and internal and external materials that need to meet the bar of the most senior people in the room

High attention to detail and organization. You are the kind of person who makes sure the details no one else is tracking are handled

High ownership and a bias to action. You would rather unblock the team by fixing something yourself than wait for someone else to do it

Comfort operating across extremes: one hour on the floor of the office, the next with a senior government stakeholder or a top-tier investor

Willingness to travel when needed, including to customer sites

Qualifications (preferred)

Experience at a high-growth startup, ideally as one of the first non-engineering hires

Experience setting up finance and people ops systems from scratch

Experience with early-stage fundraising

Experience in defense tech, national security, or government contracting is a plus, but not required

If there is a fit, we will schedule behavioral and case-based interviews. The final step is an onsite in our office, where you will work on a scoped project, discuss ideas, and work with the wider team.

Original posting on Valthos's site ↗

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