R&D / Iron Complex Development

Job Description – R&D / Iron Complex Development

Position: R&D Executive / Scientist – Iron Complex Development

Department: R&D / Process Development

Experience: 5–7 Years

Qualification: M.Sc. / M.Tech. in Chemistry, Pharmaceutical Chemistry, or related field

Industry: Pharmaceutical / API

Location: Vapi, Gujarat

Job Purpose

We are looking for an experienced R&D professional with hands-on experience in iron complex/API development . The candidate will be responsible for product development, process optimization, troubleshooting, scale-up, and technology transfer of iron-based pharmaceutical products.

Key Responsibilities

• •Develop and optimize ferric and ferrous iron complexes and iron-based APIs.
• •Work on Iron Sucrose, Iron Polymaltose/Iron Hydroxide Polymaltose, Ferric Carboxymaltose (FCM) and related iron complexes.
• •Design and execute laboratory and pilot-scale experiments .
• •Optimize reaction parameters including pH, temperature, reaction time, concentration, addition sequence and oxidation/reduction conditions .
• •Optimize critical quality attributes such as molecular weight, particle size, PDI, iron content, oxidation state, solubility, stability and purity .
• •Troubleshoot issues related to precipitation, aggregation, colour variation, molecular weight, yield and batch-to-batch consistency .
• •Interpret analytical results from GPC, particle-size analysis, Zeta potential, iron assay and other characterization techniques .
• •Prepare process parameters, batch procedures, development reports and scale-up protocols .
• •Support pilot trials, process scale-up, technology transfer and validation batches .
• •Evaluate raw materials and their impact on process performance and final product quality.
• •Coordinate with QC, QA, Production, Analytical and Engineering teams.
• •Identify opportunities for process improvement, yield improvement, cost reduction and quality enhancement .
• •Maintain proper laboratory records and technical documentation.

Required Skills

• •Strong practical knowledge of iron chemistry and coordination/complex chemistry .
• •Hands-on experience in ferric and/or ferrous iron complex development .
• •Knowledge of iron oxidation/reduction chemistry .
• •Strong understanding of process parameters and their impact on product quality.
• •Experience with iron-carbohydrate and iron-polymer complexes .
• •Experience in process optimization and scale-up .
• •Strong troubleshooting and problem-solving skills.
• •Ability to interpret analytical data and correlate process parameters with product quality .
• •Good technical documentation and report-writing skills./

Preferred Experience

Candidates with hands-on experience in pharmaceutical/API development of parenteral or injectable iron products will be preferred.

Ideal Candidate

A technically strong R&D professional who can independently handle the complete development cycle:

Skills:- R&D, Iron Complex Development, iron complex, Iron, API, Pharmaceutics, Pharmaceutical, M.Sc. and Chemistry