Scientist / Sr. Scientist In Vivo Translational Sciences

Our Mission

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.

For more information, see our website at altoslabs.com.

Our Value

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Diversity at Altos

Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment.

What You Will Contribute To Altos

An exciting opportunity is available for a Scientist to join the In Vivo Translational Sciences team within Drug Discovery and Development Sciences (3DS) at Altos Labs.

We are seeking a dedicated and highly skilled Scientist for our In Vivo Pharmacology Operations. In this role you will be responsible for the full lifecycle of in vivo pharmacology studies — from design and protocol development through execution, analysis, and interpretation — to support the progression of our therapeutic programs. This role demands a solid understanding of in vivo research methodologies and the ability to operate in a complex, fast-moving research environment.

Responsibilities

Lead the full lifecycle of in vivo pharmacology studies across multiple projects — providing in vivo pharmacology and physiology expertise from study design and model selection through dosing and in-life monitoring, tissue collection and processing, data analysis, interpretation, and reporting of results to program teams

Contribute to selection of pharmacodynamic and target-engagement readouts

Contribute to building translational strategy by leveraging in vivo research for target validation and candidate progression

Develop, characterize, and implement new animal models; including models of fibrosis and other age-related pathologies

Evaluate and implement new technologies, platforms, and best practices for in vivo research to enhance study efficiency and quality

Execute studies in both mice and rats, including conducting survival surgeries to establish rodent models using aseptic technique

Occasionally execute downstream ex vivo analyses

Maintain detailed documentation of all studies in the electronic lab notebook to ensure data integrity and traceability

Collaborate with cross-functional partners across discovery biology, pharmacology and assay sciences, DMPK, and technology development to advance therapeutic programs

Ensure all in vivo work meets IACUC-approved protocols and uphold the highest ethical standards in study conduct

Contribute to a team culture that promotes continuous improvement, ownership, professional growth, and inclusion

Who You Are

Ph.D. in biological sciences with a minimum of 3-5 years (Scientist) and 6+ years (Sr. Scientist) of industry experience in a drug discovery and development setting

Extensive expertise with all aspects of in vivo rodent research (various dosing routes, anesthesia, surgical procedures, necropsy, tissue processing, etc.) in both mice and rats

Strong commitment to animal welfare and a 3Rs-centered approach to experimental design

Excellent communication skills for effective collaboration with internal teams and external CRO partners

Exceptional organizational skills, strong attention to detail, and the ability to work independently and collaboratively in a dynamic environment

Demonstrate creative thinking and a proactive, solution-oriented mindset; able to design, troubleshoot, and refine complex in vivo studies with resourcefulness and innovation

High-level problem-solving ability with strong analytical thinking and the capacity to make practical, data-driven decisions

Hands-on experience with molecular and cell biology techniques (RNA/DNA extraction, PCR, Western blot, ELISA, and small molecule/biologic assays)

Willingness and ability to work in a lab/vivarium environment for the majority of working hours, including supporting weekend study needs

Preferred Qualifications

Experience working across diverse therapeutic modalities, including small molecules, biotherapeutics, nucleic acid therapeutics, and gene therapy is highly desirable

Experience analyzing age-related diseases/deficits in animal models, including fibrosis, inflammation, metabolic disorders or neurodegeneration

The salary range for Redwood City, CA

Scientist II, In Vivo Pharmacology : $148,400 - $190,300

Senior Scientist I, In Vivo Pharmacology $171,400 - $219,700

Exact compensation may vary based on skills, experience, and location.

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Equal Opportunity Employment

We value collaboration and scientific excellence.

We believe that a culture of belonging are foundational to scientific innovation and inquiry. At Altos Labs, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining an inclusive environment.

Altos Labs provides equal employment opportunities to all employees and applicants for employment, without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. Altos prohibits unlawful discrimination and harassment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Thank you for your interest in Altos Labs where we strive for a culture of scientific excellence, learning, and belonging.

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