Senior Director - Medical Affairs

Job Description:

Mandate

• •Design fidelity in the clinic
• •• Own investigator training on the tissue-state eligibility framework, the structural grading scales, and patient-reported outcome administration, across all participating sites and indications.
• •• Build and run the grading calibration and inter-rater reliability programme: reference materials, calibration rounds completed before first patient in, pre-specified reliability thresholds, periodic re-calibration, and ongoing drift monitoring.
• •• Own the adjudication pathway for discordant and borderline gradings.
• •• Maintain criteria-integrity surveillance: every eligibility decision documented against the framework, every borderline case and deviation escalated.
• •Investigator, expert and institutional engagement
• •• Act as principal scientific relationship owner for UAE clinical partners and health-authority stakeholders.
• •• Sustain and deepen the established investigator relationships in India and Japan.
• •• Build the investigator network for the pre-planned second-stage indication.
• •Evidence and publication strategy
• •• Own the publication plan for a study intended to be a landmark first-in-human result, and drive it to delivery.
• •• Set congress and scientific-communication strategy.
• •• Hold scientific-narrative consistency across every output — abstracts, posters, manuscripts, investigator materials, and health-authority correspondence.
• •Regional medical and access foundation
• •• Support the epidemiology and market-access groundwork underway with regional partners.
• •• Build the medical foundation for eventual payer and reimbursement engagement across MENA.

Scope boundaries

These are stated up front, deliberately. This role does not own:

Clinical operations — regulatory submissions, site contracting and initiation, monitoring, data management and vendor oversight sit with the CRO, under the CEO.

Study design — the protocol, endpoints, eligibility criteria and statistical architecture are set and, in material part, filed as intellectual property. This role executes fidelity to the design; it does not redesign it.

Intellectual property and regulatory strategy, which sit with the CEO and counsel.

Financing and investor engagement.

Requirements

Medical degree, with 10+ years in medical affairs and substantial depth in ophthalmology.

Demonstrated ownership of multi-site, multi-investigator scientific standardisation or diagnostic-competency programmes — at scale, and with measurable outcomes.

Regional medical strategy experience across emerging, Middle East or Asia-Pacific markets.

A track record of building durable scientific relationships with academic and government institutions.

Willingness to be present in the UAE as the programme requires — including sustained presence around site initiation, investigator calibration, and the first-patient-in period.

This position involves travel across the UAE, Bangalore, and Delhi.