Senior Program Manager

Career Category

Project Management

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Program Manager

What you will do

Let’s do this. Let’s change the world. The Senior Program Manager partners closely with an R&D Quality Associate Vice President for Clinical & Research Quality and Senior Directors for R&D GxP Audit and Operational Excellence to drive execution of strategic priorities. This role integrates strategic planning, operational excellence, organizational effectiveness, communications, portfolio coordination and transformation to enable leadership focus on business priorities. In close partnership with the RDQ Strategy & Performance and Operations (SPO) Director, this role helps translate enterprise and RDQ strategic priorities into coordinated operational execution across supported capabilities while ensuring consistent approaches, templates, governance, and business processes across the organization.

Key responsibilities include:

Strategic Planning & Execution

Partner with capability leaders in Clinical & Research Quality, R&D GxP Audit and Operational Excellence to develop and execute annual strategic priorities, operating plans and measurable deliverables

Coordinate execution of RDQ priorities across supported capabilities through standardized templates, governance, and business processes to ensure consistent delivery

Monitor organizational objectives, milestones and dependencies

Identify operational risks and recommend mitigation strategies

Support the Operational Excellence Senior Director in centrally coordinating and tracking emerging and ongoing business initiatives and due diligence/mergers & acquisitions to enhance RDQ visibility and inform functional resource planning across RDQ

Business Operations

Partner with capability leaders in Clinical & Research Quality, R&D GxP Audit and Operational Excellence to co-lead planning and execution of leadership team meetings and organizational forums (e.g. Therapeutic Area portfolio reviews, performance management reviews)

Assist in development presentations for governance, dashboards, decision materials, and meeting content

Drive follow-up of leadership decisions and action items

Coordinate preparation of standardized business materials, executive updates, operating review content, and leadership communications using common RDQ templates and formats to promote consistency and efficiency

Serve as the primary operational liaison between supported capability leadership and the Strategic Performance & Operations Director to coordinate information flow, deliverables, and business planning activities

Functional Transformation and Program Management

Coordinate key functional initiatives related to Clinical & Research Quality, R&D GxP Audit and Operational Excellence

Partner with the Strategic Planning & Operations Director to operationalize enterprise initiatives within supported capabilities, ensuring strategic direction is translated into actionable implementation plans

Monitor timelines, deliverables, and interdependencies

Facilitate strategic workshops and planning sessions for key functional initiatives

Support implementation of transformation (e.g. new operating models, organizational changes)

Engage with Continuous Improvement for Organizational Change Management strategies and best practices

May support special projects, as assigned by manager

Operational Excellence

Improve organizational effectiveness for Clinical & Research Quality, R&D GxP Audit and Operational Excellence through standardized processes by implementing standardized business processes, governance practices, templates, and tools that enable consistent execution across RDQ

Build and/or manage organizational knowledge repositories (e.g. SharePoint, MS Teams)

Support workforce planning and organizational capacity planning

Monitor organizational health metrics and recommend improvement actions

Leadership Support

Serves as a trusted partner to capability leadership by translating strategic direction into coordinated execution plans, tracking progress, and facilitating alignment across functions

Collaborates closely with the Strategic Performance & Operations director and peer Program Managers to ensure enterprise priorities, governance activities, and leadership requests are executed consistently across RDQ

Thinks strategically while executing operationally

Applies continuous improvement mindset and problem-solving skills in proactively identifying opportunities to improve operational excellence

Ability to navigate ambiguity and changing priorities with agility in a fast-based, dynamic environment

Influences without authority

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is an individual with these qualifications

Basic Qualifications:

Doctorate degree and 2 years of relevant experience (program management, business operations, quality assurance, R&D) OR

Master's degree and 4 years of relevant experience (program management, business operations, quality assurance) OR

Bachelor's degree and 6 years of relevant experience (program management, business operations, quality assurance, R&D) OR

Associate's degree and 10 years of relevant experience (program management, business operations, quality assurance, R&D) OR

High school diploma/GED and 12 years relevant experience (program management, business operations, quality assurance, R&D)

Preferred Qualifications:

Experience supporting leadership teams

Advanced skills in program or portfolio management in a matrixed organization

Demonstrated ability to manage multiple priorities while maintaining attention to detail

Experience developing strategic roadmaps and operating plans

Proven track record with successfully integrating global teams with effective collaboration and high emotional intelligence

Proficiency with collaboration and AI tools (e.g. Microsoft PowerPoint, Excel, Teams, SharePoint, ChatGPT, Copilot)

Exceptional written and verbal communication skills

Pharmaceutical, biotechnology, or healthcare industry experience, including knowledge of R&D quality and risk management, preferred

Lean Six Sigma and PMP (Project Management Professional Certification

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a T