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Tempus

Structural Biologist III

Aliso Viejo

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hirly's read of this role

Seniority
Senior
Stated salary
$120,000 – $170,000 per year
Country
US
Work mode
On-site / unstated
First seen by hirly
27 Sept 2026

Derived automatically from the posting. Upload your resume above to see how the role scores against it.

the posting

Compensation:

$120,000 - $170,000



 Role Overview

The Structural Biologist III collaborates across biology, bioinformatics, software engineering, and clinical teams to design tools and methodologies leveraging biomolecular structural data to guide clinical decisions.

Key Responsibilities

Provide structural biology support for variant analyses through structure-function relationship interpretation.

Develop novel methods, protocols, and tools for structural modeling, molecular dynamics, and clinical variant assessment on internal platforms.

Partner with statisticians and data scientists to validate algorithms and data collection workflows.

Coordinate cross-functional efforts across Bioinformatics, R&D, and reporting teams for clinical research projects.

Write testable, production-grade code adhering to SDLC standards and code review best practices.

Maintain technical documentation, SOPs, and knowledge bases while mentoring junior staff.

Direct and lead the structural team through both soft and explicit leadership ensuring timely project completion

Support, inform, and educate leadership and stakeholders about project progress and blockers.

Qualifications & Competencies

Education: PhD in computational biology, structural biology, biophysics, bioinformatics, or equivalent.

Experience: Minimum 5 years of R&D experience in computational structural biology or related fields, including at least 2 years of post-doctoral or industrial experience and 2 years management experience.

Technical Skills: Fluency/proficiency in scripting/languages (Python, R, Perl, C/C++, Java, SQL) and bioinformatics/modeling software. Strong background in systems biology, molecular dynamics, and experimental techniques (X-ray, Cryo-EM).



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Equal Opportunity Employer

This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.

Original posting on Tempus's site ↗

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