Tempus
Structural Biologist III
Aliso Viejo
Get past the screening software and onto a recruiter's desk
hirly rewrites your resume for this job — matching the keywords and skills in the posting, moving your most relevant experience to the top, and writing a cover letter to fit. About 30 seconds.
- Keywords matched to this posting
- Fit score before you apply
- Cover letter included
Matched against 2.3M live jobs from 200,000+ employers in 200+ countries.
Tailor my resume for this job →hirly's read of this role
- Seniority
- Senior
- Stated salary
- $120,000 – $170,000 per year
- Country
- US
- Work mode
- On-site / unstated
- First seen by hirly
- 27 Sept 2026
Derived automatically from the posting. Upload your resume above to see how the role scores against it.
the posting
Compensation:
$120,000 - $170,000


 Role Overview
The Structural Biologist III collaborates across biology, bioinformatics, software engineering, and clinical teams to design tools and methodologies leveraging biomolecular structural data to guide clinical decisions.
Key Responsibilities
Provide structural biology support for variant analyses through structure-function relationship interpretation.
Develop novel methods, protocols, and tools for structural modeling, molecular dynamics, and clinical variant assessment on internal platforms.
Partner with statisticians and data scientists to validate algorithms and data collection workflows.
Coordinate cross-functional efforts across Bioinformatics, R&D, and reporting teams for clinical research projects.
Write testable, production-grade code adhering to SDLC standards and code review best practices.
Maintain technical documentation, SOPs, and knowledge bases while mentoring junior staff.
Direct and lead the structural team through both soft and explicit leadership ensuring timely project completion
Support, inform, and educate leadership and stakeholders about project progress and blockers.
Qualifications & Competencies
Education: PhD in computational biology, structural biology, biophysics, bioinformatics, or equivalent.
Experience: Minimum 5 years of R&D experience in computational structural biology or related fields, including at least 2 years of post-doctoral or industrial experience and 2 years management experience.
Technical Skills: Fluency/proficiency in scripting/languages (Python, R, Perl, C/C++, Java, SQL) and bioinformatics/modeling software. Strong background in systems biology, molecular dynamics, and experimental techniques (X-ray, Cryo-EM).


 PRIVACY NOTICES
To review Ambry’s Privacy Notice, Click here: https://www.ambrygen.com/legal/privacy-policy
To review the California privacy notice, click here: California Privacy Notice | Ambry Genetics
To review the UKG privacy notice, click here: California Privacy Notice | UKG
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.
Similar jobs
Want this one?
Upload your resume and hirly rewrites it for this job and writes the cover letter — in about thirty seconds, before you sign up.
Tailor my resume for this job