US Hem Endo Portfolio & Strategy Lead

ROLE SUMMARY

This is an exciting opportunity to join the US Hematology and Endocrinology franchise, one of the most rapidly growing businesses across US Commercial Division. The franchise comprises three distinct therapeutic areas including Pfizer’s long-standing presence in Endocrinology and rare bleeding disorders with Hemophilia and Sickle Cell Disease.

The US Hematology and Endocrinology Portfolio and Strategy Lead will serve a critical role for the US Hematology and Endocrinology franchise, shaping strategy and maximizing performance across a diverse and dynamic portfolio. This is a unique opportunity to drive impact across a portfolio spanning every stage of the brand lifecycle; from early-launch growth brands (Hympavzi, Ngenla), to mature core brands (Factor, Genotropin), to osivelotor, our pipeline asset in development for Sickle Cell Disease. This role will be responsible to define the strategic vision, advance key franchise imperatives, and inform portfolio planning and resource allocation to ensure short and long-term success of the franchise. The lead will also manage the operational agenda and performance reporting for the franchise team. The role will require close collaboration with the brand leads, their marketing teams and cross-functional partners to enable effective portfolio planning and execution across the entire franchise.

This position requires commercial expertise, strategic acumen, strong analytical and organizational skills, with a focus on executional excellence and exceptional communication. The successful candidate should be a self-starter with proven track record of exceptional enterprise leadership and cross-functional collaboration, demonstrating ability to prioritize and operate with high agility to set up the franchise team for success.

Reporting to the VP, US Rare Hematology & Endocrinology Franchise Lead, the Portfolio and Strategy Lead will serve as a key member of the Marketing Leadership Team, elevate team effectiveness and act as a champion of team culture.

ROLE RESPONSIBILITIES

Lead portfolio strategy, planning, and execution. Partner with brand leads, their marketing teams and cross-functional partners to enable focus on executional excellence and delivery of financial and operational targets

Identify strategic initiatives to advance franchise priorities and unlock portfolio growth. Lead identified strategic initiatives from inception to delivery, establishing effective work groups, delivery plans, performance metrics and execution

Own performance reporting and coordination in partnership with Finance and IIS leads, including monthly financial performance updates and senior leadership updates

Identify key performance trends and drivers, data, competitive intelligence and customer insights to inform brand planning, development of portfolio goals and key performance indicators. Collaborate with enablement partners in development of structured frameworks and metric based dashboards

Identify drivers/barriers of performance in partnership with leadership and cross-functional partners and develop mitigation strategies to address performance gaps

Guide development of Strategic and Operating Plans, financial planning, quarterly earnings submissions and responses to other leadership/investor relations requests

Optimize resource allocation across franchise assets and functions in partnership with the Hem Endo leadership team and customer-facing leads

Advance the AI, marketing transformation and innovation efforts for the franchise in close collaboration with cross-functional partners and CMO

Play a key role in US Hem Endo leadership team and elevate franchise team effectiveness through planning of LT offsites, team offsites, and identification and planning of purpose-built all hands meetings and trainings

Act as a champion of team culture by cultivating growth and development, key capabilities and culture initiatives

BASIC QUALIFICATIONS

8+ years of pharmaceutical industry, commercial or healthcare consulting experience required

Previous US marketing experience strongly preferred

Rare disease or specialty experience preferred

BA/BS degree required, MBA or other advanced degree highly desirable

Proven track record in developing, executing and measuring complex marketing programs that drive performance

Demonstrated ability to successfully navigate whitespace and complex stakeholder maps to develop novel solutions

Demonstrated ability to work effectively with varied internal stakeholders to identify key customer insights and translate into actionable strategies

Solid business acumen and organizational skills with excellent interpersonal communication and negotiation skills for a wide variety of audiences, including senior management

Strong people and/or matrix management and influencing skills even without direct reporting relationships

Proven track record of operating in a fast-paced, high energy environment

Strong analytical skills; detail and action oriented

Self-motivated and a team player

Demonstrated ability to manage and deliver results on multiple, complex, competing projects in a deadline-oriented environment

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact

LAST DAY TO APPLY: 10/06/2026

The annual base salary for this position ranges from $189,200.00 to $315,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.


This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.



Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will