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Unlearn

AI Engineer

San Francisco

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hirly's read of this role

Seniority
Mid level
Stated salary
$145,000 – $180,000 per year
Country
US
Work mode
On-site / unstated
First seen by hirly
7 Nov 2026

Derived automatically from the posting. Upload your resume above to see how the role scores against it.

the posting

Our Mission

Every day, people are waiting for a diagnosis, for a treatment, for a chance. Our mission is to help life-saving treatments reach patients faster.

That isn’t an abstraction to us. It’s the reason Unlearn exists, and it’s why the pace and rigor of our work matter so much.

What We Do

Unlearn is transforming clinical development by making every trial smarter. We partner with biopharmaceutical companies to redesign how clinical trials are planned, conducted, and analyzed. We use data, AI, and digital twins to make studies faster and more robust.

A digital twin is a comprehensive prediction of a patient’s expected outcomes under a defined standard of care. It is generated by machine learning models built on our proprietary technology. Leading pharma and biotech companies trust us to deliver scientifically rigorous work on studies where the stakes are high and the timelines impact patients.

Where We’re Going

Our goal is to become the gold standard for AI-driven clinical development. Getting there takes disciplined execution and data, models, and AI that is implemented with partners using a strong engineering foundation that holds up in a regulated, compliance-heavy environment. We’re building durable advantages rooted in science and innovative technologies, and that foundation is what will make our leadership last.

Our Values

Accountability, Agility, and Acceleration describe how we work with each other every day. Fulfilling our mission depends on all of us doing our best work, and it’s on all of us to build and protect the culture that makes that possible.

  • Accountability: We own outcomes, not just tasks
  • We take responsibility for results, make decisions with urgency, and follow through on our commitments. When things don’t go as planned, we say so. We surface issues early, learn, iterate quickly, and move forward without blame. We give and receive feedback that is clear, direct, and actionable.
  • Agility: We follow the evidence
  • Drug development and AI evolve rapidly. We stay curious, embrace new information, and change course when the evidence changes. We keep a close eye on where the industry is heading and build technology flexible enough to adapt when new data or opportunities arise. We value speed of learning over being right.
  • Acceleration: We create momentum
  • Our mission is to accelerate the development of new medicines, and that starts with how we work. We simplify, prioritize, and execute with urgency. Unlearners own the problems in front of them and are empowered to solve them. That helps our customers, our teammates, and our company move faster without sacrificing scientific rigor.

About Unlearn

Unlearn was founded in 2017 by a team of world-class machine learning scientists and is headquartered in San Francisco. We’re backed by top-tier investors including Altimeter, Insight Partners, Radical Ventures, 8VC, and DCVC. We have substantially advanced AI technology for clinical trials, including regulatory-grade applications, and are embedded in multiple clinical trials with top Pharma and Biotech companies.

AI Engineer. Our Science organization leads Unlearn’s efforts to build new capabilities across machine learning, statistics, and AI tools that help our teams create and deliver digital twin solutions to customers. This first-of-its-kind role at Unlearn will be responsible for scaling the use of agents for core business problems and deliver impact in efficiency and extensibility. Successful AI Engineers at Unlearn will be entrepreneurial in their approach; feeling a strong sense of end-to-end ownership of their mission, they collaborate heavily and investigate broadly to find the right tools and techniques to help their teams succeed.

Responsibilities include:

Build AI agents, skills, and tools that are core components of our workflows to create and deliver digital twins to customers

Build infrastructure, harnessing, and governance systems to manage agentic workflows in line with regulatory and compliance requirements

Collaborate with scientists across research, development, and delivery teams to define and build AI-centric solutions

Work across teams to gain user feedback and increase adoption of new tools

Clearly communicate capabilities and use to internal and external stakeholders

Stay up to date with developments in AI tooling to inform Unlearn’s work

Minimum requirements:

B.S. in computer science or engineering, physics, mathematics, or a related field.

Prior experience working with healthcare or clinical machine learning applications.

2+ years of experience developing AI skills, agents, and tools and applying them to solve real-world problems.

Experience with AI systems, from infrastructure through agent creation and use.

Experience with AWS cloud computing services.

Evidence of successful execution of AI projects in an industry setting.

Benefits & Perks

The following benefits and perks are for full time roles only.

Meaningful equity participation

100% company-covered medical, dental, & vision insurance plans for you and your dependents

401(k) plan with matching

Flexible PTO plus company holidays

Annual company-wide break December 24 through January 1

Commuter and Wellness benefits

Tech stipend

Paid Parental Leave

Unlearn is an equal opportunity employer.

At Unlearn, we are committed to building a diverse and inclusive workplace, because inclusion and diversity are essential to achieving our mission. If you’re excited about this role, and your past experience doesn’t align perfectly with every qualification in the job description, we encourage you to apply nevertheless.

Original posting on Unlearn's site ↗

Listed on hirly, a job board. hirly is not the employer: Unlearn is hiring for this role.

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