Biochemist II - GMP Recombinant Protein Manufacturing

Job Title

Biochemist II - GMP Recombinant Protein Manufacturing

Location(s)

San Diego - BioLegend

About Us

Revvity is a developer and provider of end-to-end solutions designed to help scientists, researchers, and clinicians solve the world’s greatest health challenges. We pair the enthusiasm of an industry disruptor with the experience of a longtime leader. Our team of 11,000+ colleagues from around the globe are vital to our success and the reason we’re able to push boundaries in pursuit of better human health.

Find your future at Revvity

Job Summary

This GMP recombinant protein Biochemist at BioLegend will primarily be responsible for performing protein purification, conjugation, formulation, and quality control for GMP product release. This position will assist in GMP protein manufacturing for GMP product s . The position plays an important part in the success of the robust GMP recombinant protein product manufacturing and will actively support team members in managing raw material, inventory , and batch records through efforts collaborating with other departments such as manufacturing, quality assurance, and quality control teams.

The Biochemist will perform purifying recombinant proteins using various preparative chromatography methods and separation using methods such as IMAC, size exclusion, and ion exchange , conjugation and formulate the recombinant proteins according to standard operating procedures compliant with ISO and GMP regulation .

This position will also support a variety of cross-function manufacturing tasks including work order processing and closure of pilot lots related to product release or validation.

His/her role also assists in activities for technical support, document control, validation, training, nonconformance, and CAPA systems.

Essential Functions

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

• •Following standard procedures to conduct recombinant protein or antibody purification using affinity matrix such as IMAC and Protein A Sepharos e.
• •Following standard procedures to conduct protein conjugation and polishing using various types of chromatography and AKTA FPLC.
• •Conduct the in-process quality testing such as purity analysis, endotoxin t esting for the in-house made or customized bulk material of finished goods .
• •Support internal s afety and regulatory compliance audits
• •Support equipment operation training and validation activities for new process and equipment validation
• •Provide benchwork support for product releasing or troubleshooting of complicated manufacturing problems in recombinant protein production to ensure sustainable manufacturing design
• •Support reviewing of quality system documents and corrective actions (NCR, or CAR) to ensure laboratory setting and procedures are in compliance with ISO9001:2008/ 13485:2016
• •Proactively identify opportunities to improve current manufacturing procedures in order to increase efficiency and consistency to ensure QA compliance in traceability and equivalency.
• •Other projects or responsibilities may be required.

Minimum Qualifications – Education and Experience

Bachelor of Science in Life Science or related area.

Preferred Qualifications – Education and Experience

Bachler's Degree in Life Science or related area with at least 2 years of working experience in related biotech protein or antibody product manufacturing.

Extensive experience in protein or antibody purification .

Experienced in purification and formulation of recombinant protein or antibody.

• •Exper ienced in manufacturing under ISO/GMP environment.
• •Demonstrated ability to be detail-oriented, organized and work well in small work groups
• •Able to perform basic computer operations such as MS Office and Outlook and other computer-based software ​

Work Environment & Physical Demands

Lab

While performing the duties of this job, the employee regularly works in a laboratory environment with occasional data entry on a computer. Occasional exposure to a warehouse environment.

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

While performing the duties of this job, the employee is regularly required to use hands and fingers to handle, feel, or operate objects, tools or controls, and reach with hands and arms. The employee is frequently required to stand, talk and hear.

The base salary range for this full-time position is $20.00 - 30.00/hr. This range reflects the minimum and maximum target for a new hire in this position. The base pay actually offered to the successful candidate will take into account internal equity, work location, and additional factors, including job-related skills, experience, and relevant education or training. Your recruiter can share more about the specific salary range for your preferred location during the hiring process.

Please note that base pay is only one part of our total compensation package and is determined within a range. This range allows for the successful candidate to have an opportunity to progress within the position and develop at our company. This base pay range does not take into account bonuses, equity, or other benefits which may be applicable and are dependent on the level and position offered.

What do we offer?

We provide competitive and comprehensive benefits to our employees. Below are some highlights of our benefits:

Medical, Dental, and Vision Insurance Options

Life and Disability Insurance

Paid Time-Off

Parental Benefits

Compassionate Care Leave

401k with Company Match

Employee Stock Purchase Plan

Learn more about Revvity’s benefits by visiting our Bswift page. Log-In instructions are provided towards the bottom of the Bswift page.

*For benefit-eligible roles only. Part-time and temporary roles may not be eligible for all benefits listed. Please reach out to your recruiter for more information.

Revvity is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to any characteristic or status protected by applicable federal, state, and/or local laws. If you are an applicant with a disability that requires reasonable accommodation to complete any part of the application process or are limited in the ability—or unable to use—the online application system and need an alternative method for applying, you may contact OpenJobs@revvity.com .