CLINICAL PROJECT MANAGER II – IMMUNOLOGY (Sponsor Dedicated/ Remote- US)

CLINICAL PROJECT MANAGER II – IMMUNOLOGY (Sponsor Dedicated/ Remote- US)

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives.

Discover what our 29,000 employees, across 110 countries already know:

WORK HERE MATTERS EVERYWHERE

Why Syneos Health

• •We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• •We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
• •We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we’re able to create a place where everyone feels like they belong.

Job Responsibilities

CLINICAL PROJECT MANAGER II – IMMUNOLOGY

Sponsor Dedicated | Remote – United States

Are you passionate about advancing innovative therapies for patients living with autoimmune and inflammatory diseases? We are seeking experienced Clinical Project Managers with strong global immunology clinical trial experience to join a high-performing sponsor-dedicated team supporting a diverse portfolio of immunology studies across multiple indications and phases of development.

This is a fully remote, US-based opportunity, with up to 25% travel, where you will play a critical role in the operational leadership and execution of global clinical trials. We are specifically seeking professionals with 3+ years of hands-on Clinical Project Management experience leading global immunology studies and collaborating with cross-functional teams, vendors, and international stakeholders.

WHAT YOU'LL DO

As a Clinical Project Manager II, you will help drive the operational execution and delivery of global immunology clinical trials, ensuring studies are conducted efficiently, compliantly, and according to established timelines.

Key Responsibilities

Support and partner with Clinical Study Leads and cross-functional study teams on global immunology trials

Lead day-to-day study management activities across study startup, conduct, maintenance, and closeout

Manage study timelines, deliverables, risks, and issue resolution

Oversee external vendors, CROs, central laboratories, specialty providers, and other study partners

Coordinate Clinical Team meetings and drive action item follow-up

Support study-level planning, forecasting, and operational strategy execution

Monitor study performance metrics and proactively identify areas requiring intervention

Ensure inspection readiness and compliance with applicable regulations and sponsor requirements

Collaborate with stakeholders across Clinical Operations, Data Management, Biostatistics, Medical Monitoring, Regulatory Affairs, Safety, Supply Chain, and Quality

Contribute to study status reporting and executive-level communications

Support achievement of study milestones, enrollment targets, database locks, and study closeout activities

Travel up to 25%

WHAT YOU WILL BRING

Required Qualifications

Bachelor's degree in a scientific, healthcare, or related field

3+ years of Clinical Project Management experience supporting global immunology clinical trials

Experience managing studies across multiple countries and regions (North America, Europe, Asia-Pacific, Latin America, or other global regions)

Vendor management experience required

Strong understanding of clinical trial operations and study lifecycle management

Experience supporting Phase I, Phase II, Phase III, and/or Phase IV immunology studies

Strong working knowledge of ICH-GCP guidelines and clinical research regulations

Proficiency with Microsoft Office Suite

Ability to work effectively within global, cross-functional matrix organizations

IMMUNOLOGY THERAPEUTIC AREA EXPERIENCE

Candidates should have direct clinical trial experience supporting one or more immunology indications, including but not limited to:

Gastroenterology / Inflammatory Bowel Disease (IBD)

Ulcerative Colitis (UC)

Crohn's Disease (CD)

Autoimmune and Inflammatory Diseases

Rheumatoid Arthritis (RA)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Axial Spondyloarthritis (axSpA)

Systemic Lupus Erythematosus (SLE)

Sjögren's Syndrome

Vasculitis

Other Autoimmune Disorders

Dermatology

Plaque Psoriasis

Atopic Dermatitis (Eczema)

Hidradenitis Suppurativa

Vitiligo

Other Immune-Mediated Dermatologic Diseases

Respiratory and Allergy

Severe Asthma

Eosinophilic Disorders

Chronic Rhinosinusitis with Nasal Polyps (CRSwNP)

Allergic and Inflammatory Respiratory Diseases

Other Immune-Mediated Disorders

Rare Immunologic Diseases

Immune-Mediated Inflammatory Disorders (IMIDs)

Emerging Immunology Indications

Candidates should be prepared to discuss the indications supported, study phases, geographic scope, and their specific responsibilities on each program.

PREFERRED QUALIFICATIONS

Experience independently leading global immunology studies

Experience supporting complex, multi-regional Phase II and Phase III programs

Experience with early-phase immunology studies (Phase I/Ib)

Experience supporting biologics, monoclonal antibodies, immunomodulators, or novel immune-targeted therapies

Familiarity with CTMS, eTMF, IRT/RTSM, and clinical data review platforms

Experience working in sponsor-dedicated or FSP environments

KEY SKILLS & COMPETENCIES

Strong project management and organizational skills

Excellent communication and stakeholder management abilities

Proven ability to manage multiple priorities in a fast-paced environment

Strong risk identification and mitigation capabilities

Detail-oriented with a focus on quality, compliance, and execution

Strong collaboration skills across global teams and functions

Ability to influence without direct authority and drive accountability across study teams

CLINICAL PHASE EXPERIENCE

We welcome candidates with experience supporting:

Phase I / First-in-Human Studies

Phase I/Ib Dose Escalation Studies

Phase II Proof-of-Concept Studies

Phase II/III Registrational Studies

Phase III Global Pivotal Trials

Phase IV and Post-Marketing Studies

Experience supporting global, multi-country immunology programs through multiple phases of development is highly preferred.

WHY JOIN US?

Work on innovative immunology programs advancing new treatment options for patients with autoimmune and inflammatory diseases

Support cutting-edge therapies across inflammatory bowel disease, dermatology, rheumatology, respiratory, and other immune-mediated disorders

Join a collaborative, sponsor-dedicated team focused on operational excellence

Enjoy the flexibility of a fully remote US-based role

Expand your impact across global clinical development programs and contribute to bringing life-changing therapies to patients

If you are an experienced Immunology Clinical Project Manager with 3+ years of global