Clinical Research Coordinator II Oncology focus (Detroit, MI)

About Profound Research

Profound Research partners with community physicians to offer clinical trials as a therapeutic option for their patients. We handle all infrastructure, regulatory compliance, and administrative operations so physicians can focus on patient care. Our model gives patients access to the newest therapies while maintaining the trusted patient-physician relationship.

Our Mission: Improving Lives by Providing Advanced Therapeutic Options

Our Vision: Creating the Absolute Best Patient-Physician Experience in Clinical Research

Our Values:

Compassion: We prioritize the patient-physician relationship, ensuring every interaction is service-oriented and patient-centered.

Urgency: We work hard and practice selflessness, acting swiftly and decisively to meet the needs of our patients, partners, and colleagues.

Solution Orientation: We embrace challenges with a positive mindset, communicate directly, and identify and implement effective solutions with efficiency.

Excellence: We insist on excellence, holding ourselves accountable and empowering each other to deliver best-in-class service while maintaining the highest ethical and scientific standards.

Why This Role Exists

NRG Oncology trials answer questions that change how cancer is treated. When those trials run in a community practice, patients can join them close to home, with the oncologist they already know and trust. Profound is growing its oncology research, and NRG studies are an important part of that work.

This role is for a coordinator who already knows who cooperative group research runs. You’ll be the lead coordinator for NRG studies across our Sterling Heights and Farmington Hills sites in Michigan, working directly with our investigators and partner oncology practices. You’ll enroll patients, keep data and safety reporting current, and follow participants through treatment and long-term follow-up. Your experience will shape how Profound runs NRG trials as the program grows. Our site network handles infrastructure, quality, and administrative operations, so you can focus on running studies well.

What You’ll Do

Run NRG Studies at Your Sites

Coordinate assigned NRG Oncology trials from site activation through long-term follow-up and closeout

Screen and enroll participants through the Oncology Patient Enrollment Network (OPEN), confirming eligibility with the investigator before registration

Conduct informed consent, study visits, and protocol procedures, including blood draws where needed, and process and ship research specimens per protocol

Track treatment timelines, required assessments, and follow-up windows across the life of each study

Keep Data and Safety Reporting Current

Submit case report forms in Medidata Rave on NRG timelines and resolve queries quickly

Grade adverse events using CTCAE and report serious adverse events through CTEP-AERS within required timeframes

Maintain audit-ready source documentation and regulatory records, including CTSU regulatory submissions and the Delegation of Tasks Log

Prepare the sites for NRG audits and internal quality reviews

Partner with the Care Team

Work alongside oncologists, nurses, and practice staff so research fits into each patient’s cancer care

Serve as the main contact for NRG, the Cancer Trials Support Unit (CTSU), and Profound’s regulatory and quality teams on assigned studies

Share your NRG knowledge with colleagues as our oncology program grows

What You Bring

Essential Qualifications

Bachelor’s degree with 3+ years of clinical research experience, OR Associate’s degree with 4+ years, OR High school diploma with 5+ years and at least 1 year as a Clinical Research Coordinator

At least 1 year of hands-on coordination of NRG Oncology trials, including legacy NSABP, RTOG, or GOG trials, with enrollment through OPEN and data submission in Rave

Working knowledge of the CTSU website, CTEP-AERS, and CTCAE adverse event grading

ACRP or SOCRA certification, or ability to obtain within 6 months of hire

Strong documentation habits and comfort managing studies with long follow-up periods and strict reporting timelines

Preferred Qualifications

Experience with other NCI cooperative group trials, such as SWOG, Alliance, or ECOG-ACRIN

Background in hematology or medical oncology trials

Prior work in a community oncology research setting

Phlebotomy experience