Director, Patient Services Operations

Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.

Our lead product candidate, lysergide tartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.

Guided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.

Together we are moving psychiatry forward—beyond better, into a boundless future. Join us!

The Director, Patient Services Operations will build a best-in-class PS Operations Team supporting the successful commercial launch of DT120, working closely with Marketing, Legal, and cross-functional commercial teams to align with corporate goals. This role will be responsible for the execution of Definium’s patient support strategy across patient onboarding, treatment preparation, REMS, and ongoing support, while ensuring all initiatives meet stringent regulatory standards (e.g., FDA). This is a rare opportunity to define the operational strategy, build the team, create the culture, and shape the infrastructure for Definium’s Patient Services.

**This position must reside in Raleigh/Durham NC area.

Responsibilities:

Create operational strategy for Definium Patient Services supporting a successful DT120 commercial launch

Manage Operational Teams including Case Managers and Leaders (i.e., Supervisors)

Support development and implementation of potential REMS For DT120 via partnership with internal and external partners

Support creation of Operational infrastructure to support overall patient journey from initial engagement through post-treatment needs

Develop hiring strategy for Case Management Team include role design, required skills, needed experience, and desired mindset

Drive hiring and onboarding process for Operation Team Members

Develop, implement, and continuously improve Patient Services SOPs, operational policies, quality standards, and escalation pathways

Support creation of needed training and engagement materials (e.g., Talking Points)

Drive team culture via purposeful strategy keeping patients, teamwork, and compliance as primary focuses

Create data driven environment through actionable and impactful KPI’s, SLAs, dashboards, quality metrics, and operational performance indicators to drive continuous improvement

Establish quality monitoring programs, coaching processes, and continuous improvement initiatives to ensure exceptional patient experiences.

Translate strategy into Patient Services operational requirements

Work closely with strategy teams to create successful, innovative, and scalable strategies

Work closely with internal teams on CRM development, phone system, reporting, automation, digital capabilities supporting Patient Services and other needed infrastructure

Ensure compliance with REMS, AE reporting, and other PS related guidelines

Develop operational contingency plans supporting business continuity and launch readiness

Work across PS teams to support overall patient and customer journey

Drive overall department culture as member of Patient Services Leadership Team

Partner with Medical Affairs, Marketing, Sales, Market Access partners, and cross-functional commercial teams to align engagement strategies with broader business objectives

Translate market insights into actionable strategies that strengthen engagement, differentiation, and launch readiness

Qualifications

Bachelor’s degree in Life Sciences, Marketing, Business, Communications, or related discipline; advanced degree preferred

Minimum 10 years industry related experience required

Minimum 5 years Patient Services Operations Leadership experience required

Significant understanding of PS compliance and legal guidelines required

Experience with Patient Services CRM & Phone systems preferred

Skilled in cross-functional collaboration; intellectually curious, solutions-oriented, and effective at communicating and socializing strategic recommendations

Launch experience in the U.S. pharmaceutical market required

Experience in CNS / psychiatry, specialty pharmaceutical, or complex treatment categories preferred

Ability to synthesize complex clinical, market, and customer data into actionable strategies

Strong presentation skills and ability to influence senior, cross-functional, and agency stakeholders

Ability to travel as required; average 10–20%, with higher travel during key launch periods

The starting base pay range for this position is $180,000-$235,000, with compensation determined based on several factors including skill set, years of experience, and geographic location.

Employees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including:

100% paid health benefits including Medical, Dental and Vision for you and your dependents

401(k) program with company match and vesting after the turn of the first month after your start date

Flexible time off

Generous parental leave and some fun fringe perks!