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Capable Labs

Hardware Engineer

San Francisco

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hirly's read of this role

Seniority
Mid level
Stated salary
$110,000 – $165,000 per year
Country
US
Work mode
On-site / unstated
First seen by hirly
28 Sept 2026

Derived automatically from the posting. Upload your resume above to see how the role scores against it.

the posting

We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber.

We value speed and rigor, coupled with excitement, drive, and a strong work ethic. In an early-stage environment, we value people who can bring clarity to open-ended problems, take ownership of the next steps, and follow through with energy.

Capable Labs is a place for ambitious, high-integrity people who want to become dramatically better. You will be surrounded by people who care intensely about the work, get close feedback from the people making scientific and company-defining decisions, and have room to own increasingly important problems.

We believe excellent work should be met with meaningful reward, ownership, and trust. Responsibility is earned through contribution, not title alone: anyone who demonstrates the judgment, rigor, and follow-through to move important work forward can earn meaningful scope.

About the Role

You will help build the physical systems behind Capable’s drug-development platform. Depending on your background and the company’s priorities, your work may span automated peptide synthesis, fluid handling, laboratory instrumentation, or subcutaneous drug delivery. You will take defined subsystems from concept through prototype, test, and iteration while working closely with chemists, biologists, and software collaborators.

Responsibilities

Design and prototype electromechanical and fluidic subsystems for laboratory automation or drug-delivery hardware.

Select and integrate components such as pumps, valves, manifolds, tubing, reactors, seals, sensors, heaters, motors, transducers, controllers, batteries, or wireless modules as the application requires.

Build and debug prototypes, investigate failures systematically, and turn test results into practical design changes.

Develop controls for timing, flow, pressure, temperature, mixing, sensing, fault detection, and recovery.

Work with scientists to connect hardware performance to chemical or biological outputs such as purity, yield, reproducibility, dose delivery, safety, and sample quality.

Write clear test procedures, record results, and define acceptance criteria for the systems you own.

Contribute to the integration of instruments, analytical systems, sample tracking, and quality-control workflows.

Ideal Qualifications

Hands-on experience building, testing, or maintaining physical systems such as laboratory instrumentation, automation systems, fluidic or microfluidic devices, electromechanical hardware, medical devices, wearables, or implantables.

You may have a background in mechanical, electrical, chemical, biomedical, or bioengineering; robotics, automation, medical devices, wearables, implantables, or equivalent hands-on experience can also fit, including nontraditional paths.

Practical comfort with some combination of electromechanical systems, fluidics, sensing, controls, laboratory instruments, or automation.

A systematic approach to root-cause analysis when a device, instrument, or experiment does not behave as expected.

The ability to own a defined subsystem, communicate tradeoffs clearly, and collaborate closely with scientists and other engineers.

Curiosity and willingness to learn across disciplines; we do not expect experience in every area listed above.

Pay & Benefits

In addition to the posted salary range, we offer generous equity options.

Compensation will depend on the skills, experience, and scope of impact you bring. If your background, experience, or compensation needs fall outside this range, we are still open to a conversation based on the scope and impact you could bring.

$500+ monthly wellness budget for training, supplements, coaching, recovery, or other tools that help you perform at your best.

Healthcare: We offer a broad range of medical, dental, and vision coverage options, with Capable covering 100% of the base policy.

You will also have access to HSA, FSA, and 401K plans.

Healthy dinners with the team are provided daily.

We support visa sponsorship where appropriate, including O-1, H-1B, J-1, TN, and other employment-based pathways. Our team is already international, with members from Canada, Pakistan, Germany, Austria, Switzerland, China, India, and the United States.

Application Process

Our process is fast, transparent, and personal. We care about getting to know the person behind the application.

Initial application

First phone screen

Second phone screen

In-person work trial in San Francisco: designed to give both sides a realistic sense of working together. Get to know the founding team!

Apply Today

Curious but not sure? Apply anyway. It takes 5 minutes, and you do not need to be actively job searching to start a conversation.

Some of the best people do not map perfectly to a job description. If this sounds like a place where you could do important work, we would like to hear from you.

And if someone exceptional comes to mind, send them our way here. We read every referral carefully, and if your referral joins Capable, we’ll send you a thank-you bonus.

Equal Opportunity

Capable is an Equal Opportunity Employer; employment with Capable is governed on the basis of merit, competence and qualifications and will not be influenced in any manner by race, color, religion, gender, national origin/ethnicity, veteran status, disability status, age, sexual orientation, gender identity, marital status, mental or physical disability or any other legally protected status.

Original posting on Capable Labs's site ↗

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Hardware Engineer – Capable Labs · San Francisco | hirly.me