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Latent

Machine Learning Engineer

San Francisco

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hirly's read of this role

Role family
Data & ML
Seniority
Mid level
Stated salary
$225,000 – $300,000 per year
Country
US
Work mode
On-site / unstated
First seen by hirly
1 Sept 2026

Derived automatically from the posting. Upload your resume above to see how the role scores against it.

the posting

About Latent

Latent is the enterprise pharmacy intelligence platform, powered by a clinical agentic engine, that enables health systems to grow their pharmacy operations and serve more patients. One engine works across the pharmacy journey to identify patients who qualify for care, improve medication access, capture eligible prescriptions and support patients throughout treatment. Latent’s platform enables more than 60 leading health systems that collectively serve an estimated 70 million people. Founded by Sriram “Sri” Somasundaram and Rishabh Jain, Latent has raised $80 million from Transformation Capital, Spark Capital, Conviction, General Catalyst, Y Combinator, and others.

The Role

The Machine Learning team is responsible for building systems that run in real clinical workflows. We work on verifiable reinforcement learning at scale, mid-training and post-training of foundation models, and novel objectives derived from longitudinal patient data. We are a small group of researchers and engineers focused on pushing the frontier while shipping real systems into production, and we expect engineers to take ownership of critical systems, not components.

As a Machine Learning Engineer, you will own the design, development, and operation of production-grade ML systems that run in real clinical workflows. You will drive systems from ambiguous problem definition through to reliable production deployment, setting technical direction along the way. We are primarily hiring for senior and staff-level engineers who are comfortable owning critical systems end-to-end. This role involves owning systems that directly impact real patient outcomes.

What You'll Do

Own end-to-end ML systems, including architecture, data, modeling, evaluation, and production infrastructure

Train and fine-tune large language models (LLMs) for:

Clinical reasoning

Medical question answering

Evidence-grounded generation

Make and own tradeoffs across accuracy, latency, cost, and safety in high-stakes production environments

Develop evaluation frameworks to ensure model safety and clinical validity

Integrate ML systems into product workflows and patient-facing applications

Monitor system performance in production and iterate based on real-world usage and feedback

Define what “correct” means in ambiguous clinical workflows in collaboration with engineers and clinicians

What We're Looking For

Strong foundation in machine learning and software engineering

Track record of building and owning ML systems in production where performance, reliability, or correctness materially mattered

Experience driving ambiguous ML problems from 0→1, including problem formulation, model design, and productionization

Hands-on experience with PyTorch or similar frameworks

Ability to operate independently in high-ambiguity environments with minimal guidance

Strong product and engineering judgment — you know when to use ML, when not to, and how to scope problems accordingly

Comfort working in a fast-moving, early-stage environment

Experience working on systems where decisions have real-world consequences (e.g., healthcare, finance, infrastructure)

Nice to Have

Experience deploying LLMs in production environments

Experience building distributed systems or large-scale data pipelines

Experience working with clinical, biomedical, or other regulated datasets

Why Join Latent

Backed by top-tier investors including General Catalyst, Conviction, and Y Combinator

Work alongside a high-caliber team building products our healthcare partners love

Work on mission-critical problems at the intersection of AI and healthcare

Real ownership and visibility

High-impact role on a small, fast-growing team

Benefits

Competitive compensation, including meaningful equity

Medical, dental, and vision insurance for employee and dependents

Flexible PTO policy

Paid parental leave

Fertility and family-building stipend through Carrot

Original posting on Latent's site ↗

Listed on hirly, a job board. hirly is not the employer: Latent is hiring for this role.

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