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Tango Therapeutics

Manager, Total Rewards

Boston, MA

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hirly's read of this role

Seniority
Lead / management
Stated salary
$123,000 – $184,800 per year
Country
US
Work mode
On-site / unstated
First seen by hirly
2 Sept 2026

Derived automatically from the posting. Upload your resume above to see how the role scores against it.

the posting

Company Overview

Tango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.

Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.

This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.

The Tango labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts.

Summary:

Tango Therapeutics is seeking a Manager, Total Rewards to help design, deliver, and continuously enhance our compensation, benefits, and rewards programs. Reporting to the Senior Director, Total Rewards & HR Operations, this role will serve as a strategic partner across the organization, ensuring our programs are competitive, equitable, scalable, and aligned with Tango's mission and growth.

This position will lead key compensation initiatives while also owning the administration and evolution of Tango's health, welfare, retirement, leave, wellness, and recognition programs. The role will partner closely with Talent Acquisition, Finance, and external vendors to deliver best-in-class employee experience that supports our ability to attract, retain, and engage top talent

Your Role:

Manage and evolve Tango's compensation and job leveling framework

Conduct market benchmarking and salary surveys to support competitive pay decisions

Partner with Talent Acquisition on job pricing, offer development, and compensation guidance for new hires

Partner with annual compensation planning, merit, bonus, equity, and promotion processes

Manage Tango's employee benefits programs, including medical, dental, vision, retirement, leave of absence, wellness, and other reward offerings

Partner with brokers and vendors to evaluate plan performance, analyze utilization and cost trends, and recommend enhancements that support employee well-being and business objectives

Lead benefit renewals, open enrollment, employee communications, and ongoing vendor management

Ensure compliance with applicable compensation and benefits regulations, including pay transparency and pay equity requirements

Manage employee recognition and reward programs, including spot awards and milestone recognition

Leverage market data and compensation tools, including Radford, to provide actionable insights to leaders

Support and optimize HR systems and Total Rewards processes to improve efficiency and employee experience

Develop and deliver compensation, benefits, and workforce analytics to support leadership decision-making, measure program effectiveness, identify trends, and inform strategic Total Rewards initiatives

What You Bring:

Bachelor's degree and 5+ years of Human Resources experience, with a focus on Compensation, Benefits, or Total Rewards

Experience supporting a fast-paced biotech, life sciences, or high-growth organization

Strong knowledge of compensation programs, market pricing, salary surveys, and job architecture

Experience managing employee benefits programs, broker relationships, open enrollment, and vendor partnerships

Familiarity with regulatory requirements related to compensation and benefits administration

Proficiency with compensation data sources such as Radford and compensation benchmarking methodologies

Strong analytical, problem-solving, and communication skills

Ability to build trusted partnerships across HR, Finance, Talent Acquisition, and business leadership

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

#LI-HYBRID

Salary range

$123,000 — $184,800 USD

Original posting on Tango Therapeutics's site ↗

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