Medical Director, Clinical Science

Mavericks Wanted

When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on

In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible.

Together we define white space, push boundaries, and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma. At BridgeBio, we value curiosity and experimentation—including the ethical & thoughtful use of AI to improve clarity, speed, and quality of work.

What You'll Do

The Medical Director, Clinical Science will lead high-impact initiatives to advance patient care by identifying clinical opportunities, developing a relevant strategy with supporting scientific programs and high-impact scientific content to accelerate clinical adoption.

Working cross-functionally and with external scientific collaborators, this role will independently lead initiatives to improve patient outcomes through the interface of patient-product evidence.

The role requires a physician with clinical experience who is capable of developing scientific strategies that have the highest patient impact, generating related scientific content, leading external collaborations, and driving clinically meaningful programs from concept through execution.

Responsibilities

Clinical Strategy

Execute opportunity identification and lead high patient-impact clinical initiatives

Develop strategies to optimize patient outcomes

Translate emerging scientific opportunities into actionable clinical programs

Scientific Leadership & Content Development

Lead development of scientific content, including abstracts, manuscripts, advisory board materials, executive presentations, and scientific communications

Serve as scientific content lead for priority congresses and publication programs, partnering with Publications and Medical Information to maximize scientific impact and content amplification

Develop scientific narratives that support clinicians to optimize patient results

Clinical Programs

Support and extend the strategy for programs to address latent key clinical challenges

Design prospective observational clinical studies with external investigators with Evidence Generation, leading protocol development with a lens of clinical relevance, supporting study planning, budgets, and execution in collaboration with internal and external partners

Lead strategic scientific collaborations and translate scientific progress into executive and Board-level communications, integrating results and insights into adaptive strategies, publications, and future clinical initiatives

Strategic Scientific Partnerships

Partner with Field Medical to accelerate priority initiatives through targeted scientific engagement, leveraging strategic relationships to build alignment around key patient-oriented initiatives (e.g., women, comorbid CKD)

Support focused advisory boards, scientific roundtables, and targeted regional initiatives and programs to lend clinical expertise

Develop new scientific concepts and collaborations to expand BridgeBio’s patient impact

Where You'll Work

This is a U.S.-based remote role that will require as needed visits to our San Francisco Office, as well as periodic travel for investigator meetings and scientific congresses.

Who You Are

MD, background or experience in the cardiovascular therapeutic area a plus

Demonstrated ability to identify latent clinical and patient needs and to develop strategies and tactics to execute

Strong publication record with experience independently developing scientific content

Experience designing prospective and retrospective observational clinical studies

Strong understanding of clinical trial interpretation and evidence development

Excellent scientific writing and communication skills

Ability to independently lead complex cross-functional scientific and clinical initiatives

Demonstrated success building productive external scientific collaborations

At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.

Salary

$325,000 — $375,000 USD

As a global company, our comprehensive benefits may vary based on location. We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.

For BridgeBio Full-Time U.S Based Roles:

Financial & Rewards

Market-leading compensation

401(k) with employer match

Employee Stock Purchase Program (ESPP)

Pre-tax commuter benefits (transit and parking)

Referral bonus for hired candidates

Subsidized lunch and parking on in-office days

Health & Well-Being

100% employer-paid medical, dental, and vision premiums for you and your dependents

Health Savings Account (HSA) with annual employer contributions, plus Flexible Spending Accounts (FSA)

Fertility & family-forming benefits

Expanded mental health support (therapy and coaching resources)

Hybrid work model with flexibility

Flexible, “take-what-you-need” paid time off and company-paid holidays

Comprehensive paid medical and parental leave to care for yourself and your family

Skill Development & Career Paths:

People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility

We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, & BetterUp Coaching

We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities