Regional Director, Site Engagement & Access

Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.

Our lead product candidate, lysergide tartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.

Guided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.

Together we are moving psychiatry forward—beyond better, into a boundless future. Join us!

We are seeking to hire 2 Regional Directors, Site Engagement & Access (East and West) to build and lead a field-based team responsible for advancing treatment site readiness, supporting operational implementation, and establishing the reimbursement capabilities necessary for successful & sustainable treatment delivery.

The Regional Director will lead a team of Site Engagement and Access Leads who serve as integrated resources to sites of care, supporting both operational readiness and reimbursement needs throughout the treatment journey.

This role requires strategic, hands-on leadership with experience in market access, field reimbursement, site of care activation and complex therapy launches. The successful candidate will translate national strategy into regional execution, build strong cross-functional partnerships, and drive measurable progress in site readiness, treatment implementation, and access & reimbursement effectiveness.

Responsibilities:

Recruit, develop, coach and lead a compliant, high-performing team of Site Engagement and Access Leads responsible for both site readiness and ongoing reimbursement support

Translate national strategy into regional priorities, execution plans and measurable objectives

Oversee regional site engagement strategies to assess operational capabilities and identify barriers

Guide team in supporting site workflows, staffing, scheduling, training requirements and applicable REMS requirements

Ensure field teams effectively educate on coverage, coding, billing, and reimbursement processes, including buy-and-bill requirements

Identify and escalate complex reimbursement barriers, emerging payer challenges, and site-level financial concerns

Partner with Market Access, Patient Services, and other internal functions to develop solutions and improve site reimbursement capabilities

Ensure field reimbursement activities remain within applicable regulatory, legal, and company compliance requirements

Partner with Sales Leadership, Market Access, Medical Affairs, Training, Trade & Distribution, Patient Services, and other stakeholders to coordinate site engagement and access strategies

Provide actionable regional insights regarding site capabilities, operational barriers, reimbursement challenges, and treatment implementation needs

Support the development and refinement of field tools, training programs, reimbursement resources, and operational processes

Qualifications:

Minimum bachelor’s degree required, degree in business, healthcare administration, life sciences, or a related field preferred

Minimum 10 years of experience in pharmaceuticals, biotechnology, healthcare, or related industries required

Minimum 5 years of experience in market access, field reimbursement, patient services, site-of-care management, or healthcare operations

Launch experience is required

Experience working in a small entrepreneurial type environment

Demonstrated experience building, leading and developing field-based teams

Strong understanding of healthcare delivery systems, provider operations, and complex treatment implementation

Demonstrated knowledge of medical benefit reimbursement, including buy-and-bill models, coverage, coding, billing, and payer processes

Proven ability to execute complex field strategies and influence cross-functional stakeholders

Strong leadership, communication, analytical, and problem-solving skills

Up to 75% travel may be required based upon business needs within an assigned region

Individual compensation within the range is determined based on factors such as relevant skills, experience, qualifications, scope of the role, and other legitimate business considerations. In addition to base salary, this role may be eligible for bonus and equity opportunities. We also offer a comprehensive benefits package including health insurance, 401(k) with company match, flexible time off and additional wellness benefits and perks. Learn more about our benefits on our Careers page.

The anticipated base salary range for this position is:

$195,000 — $285,000 USD