Research Associate in Cardiovascular and Metabolic Disease Models in vitro_2 years temporary

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

pRED Cardiovascular & Metabolism, Immunology (CMI), located in Basel, Switzerland, focuses on the discovery and early development of innovative treatments for specific diseases that affect the lives of millions. In the cardiovascular and metabolism area, we are developing cutting-edge therapies to treat metabolic diseases.

We are seeking an experienced Research Associate with a strong industry background to join our Cardiovascular and Metabolic Diseases (CVM) in vitro department. In this role, you will design and execute in-vitro experiments using complex cellular models to evaluate the efficacy and safety of novel therapeutic candidates for cardiovascular and metabolic diseases.

The opportunity

Cultivation of primary cell lines from human and animal tissues, optimizing protocols for primary cell isolation, differentiation and maintenance.

Execution of functional cell based and enzymatic assays to study metabolic pathways and other relevant metabolic pathways related readouts e.g. lipolysis, glucose uptake, cAMP signaling

Experience in advanced cellular and biochemical techniques, such as cell painting, and metabolic flux analysis using Seahorse to evaluate cellular bioenergetics.

Strong knowledge of standard molecular biology techniques such as qPCR, Western Blot, Immunohistochemistry.

Analyze experimental data with statistical tools, preparing high-quality reports and presentations to communicate findings effectively.

Experience with animal handling, treatment and functional metabolic experimentation is advantageous

Who you are:

You hold a Bachelor’s or Master’s degree in biology, biochemistry, or a related field, or have completed vocational training in biology. A minimum of 3 years in a pharma industry laboratory setting is required.

You are proficient in cell culture, molecular biology, and biochemical techniques and are familiar with metabolic and/or cardiovascular cellular models.

You communicate effectively in English, both in writing and orally. Skillfully able to interact with people and have strong commitment to teamwork.

Strong organizational skills, excellent data management and record-keeping skills are required.

At Roche, we aim high to deliver life-changing healthcare solutions. If you’re ready to make a meaningful impact on patients and healthcare systems worldwide, this is the place for you.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.