Research Technician Skilled In Mouse Work

(ID: 2026-3802)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Axle is seeking a Research Technician Skilled In Mouse Work to join our vibrant team at the National Institutes of Health (NIH) supporting the National Human Genome Research Institute (NHGRI) located in Bethesda, MD.

Benefits We Offer:

100% Medical, Dental & Vision Coverage for Employees

Paid Time Off and Paid Holidays

401K match up to 5%

Educational Benefits for Career Growth

Employee Referral Bonus

Flexible Spending Accounts:

Healthcare (FSA)

Parking Reimbursement Account (PRK)

Dependent Care Assistant Program (DCAP)

Transportation Reimbursement Account (TRN)

Position Overview

The Research Technician will provide research support to NHGRI scientists through laboratory methods, procedures, and techniques in cell biology, molecular biology, biochemistry, and glycobiology. The role includes working with mouse models of Free Sialic Acid Storage Disorder (FSASD) and GNE, supporting laboratory experiments and protocols, analyzing research data, and preparing results for presentation and publication.

Additional Qualifications

Education

Bachelor's degree in Biology.

Certifications & Licenses

Biosafety Level 1 (BSL 1).

Software

Microsoft PowerPoint

Microsoft Excel

Microsoft Word

R

Skills

Mouse handling

Manuscript writing

Tissue sectioning

Data presentation

Primary cell culture

Western blotting

Deliverables

Clean equipment — Weekly

Run validation — Daily

Inspect equipment — Bi-Weekly

Meet with laboratory members to present updates — Bi-Weekly

Statement of Work Details

Work collaboratively with mouse models of FSASD and GNE in the NHGRI animal facility, including mouse breeding, observation, tissue collection, therapeutic testing, and documentation of breeding and tissue collection logistics.

Support NHGRI scientists in planning, developing, and implementing laboratory experiments and protocols.

Assist in coordinating communication with the Research Consortium on FSASD.

Perform laboratory techniques in molecular biology, biochemistry, glycobiology, and cell biology, including sterile cell culture, polymerase chain reaction (PCR), quantitative reverse transcription PCR (qRT-PCR), deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) assays, cloning, protein assays, glycobiology tools, lectin technologies, and antibody techniques.

Plan and execute in vitro and in vivo experiments, including cell culture, Western blotting, immunofluorescence, and immunohistochemistry.

Perform primary cell culture, cell separation, and quantitative and qualitative analyses.

Operate laboratory instruments, including confocal microscopes, spectrophotometers, plate readers, and other imaging equipment.

Process specimens for embedding according to established protocols.

Maintain sample inventories and storage according to outlined guidelines.

Analyze, document, and interpret experimental data; discuss results with laboratory team members.

Prepare experimental progress updates, reports, summaries, and written, tabular, and graphical presentations of findings.

Prepare data and conclusions for publication in professional journals, including publication-quality graphs.

Maintain laboratory supplies and consumables, track supply usage, and initiate purchase orders.

Clean and sterilize instruments, glassware, and equipment; support glassware washing, media preparation, and autoclaving.

Perform laboratory equipment maintenance and coordinate liquid waste container pickup.

Provide technical assistance and expertise to laboratory members and train staff in routine laboratory tests and procedures.

Develop and assist with new assays based on investigator requests and recommend new research strategies and approaches.

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: [email protected]

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range

$80,000 — $85,000 USD