AstraZeneca
Senior Automation Engineer, Laboratory Automation – Analytical Sciences
US – Santa Monica Colorado Avenue – CA
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hirly's read of this role
- Seniority
- Senior
- Stated salary
- $103,286 per year
- Country
- US
- Work mode
- On-site / unstated
- First seen by hirly
- 16 Oct 2026
Derived automatically from the posting. Upload your resume above to see how the role scores against it.
the posting
We are seeking an accomplished Senior Automation Engineer to join the Laboratory Automation team within Analytical Sciences. This fully on-site role is based in Santa Monica, California. Reporting to the Associate Director of Laboratory Automation, you will develop, implement, and optimize automation solutions for cell-based, immunological, and genomic assays. You will own deliverables, maintain momentum, and proactively communicate progress, risks, decisions, and resource needs. The role combines hands-on engineering with project execution and stakeholder management to improve assay robustness, workflow efficiency, and data quality for novel engineered cell therapy products.
Key Responsibilities
Design, build, and implement automation solutions for cell-based, immunological, and genomic assays
Program, test, and maintain Hamilton VANTAGE and other automated liquid-handling workstations
Develop and optimize liquid-handling scripts for complex bioassay workflows
Partner with scientists, engineers, and IT specialists to translate manual processes into robust automated workflows
Troubleshoot, maintain, and continuously improve automated systems to ensure reliable performance
Support the transfer of automated assay methods to Quality Control teams and external partners
Create and maintain SOPs, user guides, and technical reports
Train laboratory personnel on automation systems, workflows, and best practices
Evaluate emerging automation technologies and recommend opportunities for implementation
Qualifications
- Bachelor’s or master’s degree in bioengineering, biotechnology, mechanical engineering, electrical engineering, or a related field of hands-on experience with laboratory automation systems
- Advanced expertise with Hamilton liquid-handling platforms and VENUS software
Experience developing integrated automation workflows using scheduling software such as HighRes Cellario
Proficiency in Python, C++, or a similar programming language
Experience with cell culture, immunological assays, and flow cytometry
Knowledge of GMP requirements and experience in a regulated environment
Strong problem-solving skills, sound judgment, and attention to detail
Excellent written, verbal, and technical communication skills
Demonstrated ability to proactively communicate progress, risks, decisions, and resource needs
Proven ability to prioritize competing work, maintain focus, own deliverables, and provide clear, timely progress updates
Ability to balance hands-on engineering with project execution, stakeholder alignment, and business priorities
Preferred Qualifications
Knowledge of cell therapy development and manufacturing processes
Familiarity with QbD principles
Experience applying DoE approaches to method development
Experience with data analysis and visualization tools such as Prism, JMP, or FlowJo
Experience with computer-aided design tools such as AutoCAD or Fusion 360
Experience using 3D printing for laboratory automation applications
Experience with LIMS such as Benchling or Labguru, and their integration with laboratory automation schedulers
The annual base pay (or hourly rate of compensation) for this position ranges from $103,286.40 to $154,929.60. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Date Posted
16-Oct-2026
Closing Date
29-Oct-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
Listed on hirly, a job board. hirly is not the employer: AstraZeneca is hiring for this role.
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