Senior Director of Business Transformation - Enterprise Cell Therapy Unit

While the advertised location for this position is Boston, US - We are able to offer flexibility where the role can be based and Gaithersburg, MD and other West Coast locations will be considered where possible.

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. AstraZeneca has a multifaceted environment that cultivates collaboration and innovation to achieve our goals. We attract top minds, and we nurture and build talent.

Within the AstraZeneca Enterprise Cell Therapy Unit, our ambition is to realize the full potential of cell therapy for people living with cancer, immune-mediated and rare diseases around the world. This unit has responsibility for the value chain from discovery through to late-stage development and commercialization. We are rapidly progressing a broad pipeline of cell therapies in collaboration with AstraZeneca’s Therapeutic Area Units.

This role is a dynamic role responsible for the management of overall Business Improvement, Transformation, and Strategic Programs at a global level for within the Enterprise Cell Therapy Unit The ideal candidate for this role will be curious, creative, analytical with a natural leadership drive to bring solutions beyond immediate challenges; challenge the status quo and will have outstanding communication and influencing skills. This leader will share frequent interactions with senior leaders across Cell Therapy, as well as close collaboration with leaders of R&D and Commercial across of multiple Therapy areas. Success in this role will result in improved business decision-making, accelerated innovation, and enhanced productivity. A passion for transformation, combined with relationship-building, leadership, and communication skills will be key to success.

Key Accountabilities:

Strategic Thinking and Business Agility:

Accountable for defining and executing business transformation strategies which will enable superior quality, effectiveness and efficiency of the business; Establish and drive transformation roadmap structure and strategy.

Identify high level opportunities for process improvement and drive implementation of the key process improvement and lean initiatives that will ensure successful launch and management of multiple products and pipeline.

Drive synergies, simplification and productivity initiatives and achieve cost efficiencies for specific functions within the Cell Therapy Organizations. Lead cross functional teams to identify top operational challenges and supporting transformation programs that will strengthen supply model for autologous and allogenic modalities.

Actively collaborate with key networks across AZ and externally to gain awareness of current industry trends to contribute and influence new evolving technologies and practices. Share strategic outcomes of key strategy implementation and Business transformation projects with senior leadership teams, outlining benefits from a cost, speed and quality perspective and demonstrating the return on investment (ROI)

Build a trusting relationship with senior leaders and other key stakeholders across the enterprise to advise and influence operational transformational changes supporting 2030 bold ambition

Articulate and engage on proactive communication with key stakeholders on strategy implementation

Crucial Requirements

Bachelor’s degree in appropriate discipline

Minimum 7 years in operational strategy OR 3 years management consulting experience

Superior project management skills with demonstrated experience successfully managing a cross-functional or cross-departmental team on a sophisticated project

Comfort with ambiguity and the ability to logically structure issues and determine recommended resolutions

Demonstrated ability to set and manage priorities, resources, performance targets and project initiatives in a global environment

Operational expertise in proactive risk management and contingency planning

Conceptual, analytical, with demonstrated strategic thinking capability

Ability to work well under pressure and effectively and professionally navigate tough situations

Ability to challenge the status quo, take ownership and holds self and others accountable

Ability to influence strategically and persuade tactfully, to obtain desired outcomes while maintaining effective, positive, organizational relationships

Passion for Patients and Customers, representing the needs of multiple customers in decision making

Desirable Education, Qualifications, Skills and Experience

Masters or PhD or other advanced degree in appropriate discipline with MBA

PMP certification

Strong experience in relationship management and influencing skills

Effective problem and conflict resolution skills and proven team focus

Excellent knowledge of AstraZeneca policies, procedures and guidelines

Experience in working with senior leaders

When we put unexpected teams in the same room, we unleash bold thinking with the power to encourage life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

The annual base pay for this position ranges from $189,232 - $283,849 USD Annually. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

19-Oct-2026

Closing Date

31-Oct-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.