Senior Principal Scientist (Sr. Research Scientist), Bioanalytical

• Senior Research Scientist- Onsite, Lenexa, KS- Full-Time; Flow Cytometry
• ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.

As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.

We are excited to be seeking a new Senior Principal Scientist (Sr. Research Scientist) at ICON in Lenexa, Kansas (KS). The Senior Principal Scientist (Sr. Research Scientist) will lead and conduct scientific research aimed at advancing clinical trials and developing innovative therapies. You will manage sponsor programs, shape assay strategies, and provide expertise for new and complex modalities.

We are seeking candidates with proven method development and Spectral Flow Cytometry experience.

What You Will Do:

The Senior Principal Scientist is responsible for method development and validation for testing preclinical and clinical specimens using flow cytometry, and ligand-binding analytical methods. In addition, you will oversee transfer robust flow cytometry methods for further for bioanalytical testing.

Desired Experience (flow cytometry experience required, ligand binding experience preferred):

Flow cytometry

Experience with Spectral Flow

Panel design

Gating strategy design

Usage of cytometry software (e.g. FACSDiva, FCS express)

Ligand binding assays

ELISA, ECLIA

PK, PD, and immunogenicity

Usage of relevant software (e.g. SoftMax Pro, Watson)

Method Development

Designs and executes experiments for method development

Develops new scientific approaches to method development and communicates these to the global science team

Mentors junior scientists and advises operation on developed methods

Reviews and approves data of other scientists

Communicates with team members and management regarding project status, purpose, scheduling, problems, etc.

Lead communication with clients regarding project status.

Scientific

Maintain knowledge and skill in all techniques where you perform your work.

Provide scientific input to management and BD about new technology investments and lines of service.

Own discussions regarding scientific results with sponsors, together with project manager

Promotes ICON utilizing scientific skills through scientific communication such as external publication of posters and journal articles.

Perform R&D projects

Training of technicians on technical aspects

Mentor and train staff on scientific topics

Quality and Timely Work Execution

Takes initiative in process development and SOP/WI writing

Legible, logical and reproducible documentation of all experimentation

Has a thorough understanding and complies with GLP and other appropriate regulations

Develops rugged and economical assays

Performs data review of other scientist’s work

Sample Analysis and Assay Validation

Provides key assay input to the validation and bioanalysis team(s) to ensure successful execution

Assay troubleshooting

May perform and document maintenance, trouble-shooting and repairs on advanced instrumentation with support of service engineers or other trained supervisory personnel.

Qualifications

Read, write and speak fluent English

Spectral flow cytometry experience

10-15 years of relevant laboratory experience

MS or PhD with applicable research in a relevant scientific field, preferred

Presenter/Publisher in Regulated relevant field, preferred

#LI-KM3

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.

Benefits may include:

• •Competitive base salary and performance related incentives
• •Health and wellbeing programmes including medical, dental, and vision coverage where applicable
• •Retirement and pension plans
• •Life assurance and disability coverage
• •Employee assistance programmes and wellbeing resources
• •Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.

Visit our careers site to read more about the benefits ICON offers.

Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.

If you require reasonable accommodations during the recruitment process, please let us know or submit a request here .

Are you a current ICON Employee? Please click here to apply