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Probably Genetic

Senior Product Manager

San Francisco

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hirly's read of this role

Role family
Product management
Seniority
Lead / management
Stated salary
$155,000 – $210,000 per year
Country
US
Work mode
Remote-friendly
First seen by hirly
16 Sept 2026

Derived automatically from the posting. Upload your resume above to see how the role scores against it.

the posting

About Probably Genetic

Probably Genetic is changing the lives of patients living with severe, complex diseases. Our data platform is used by drug developers and patient advocacy groups to develop and launch treatments for these patients. Our technology discovers undiagnosed patients online, analyzes their disease state using machine learning and at-home testing, and enables compliant communication with patients. In doing so, we help patients access diagnoses, clinical trials, and treatments as early as possible.

We are a tight-knit group of hard-working, ambitious problem solvers united by a mission greater than ourselves. We do well by doing right by patients. We are developing some of the most cutting-edge solutions in healthcare, and our roadmap is packed with innovations in bioinformatics, AI, and drug development. We have built a lean, all-star team to help us bring our vision to life, and we want you to be a part of it.

Probably Genetic has raised multiple rounds of funding from Silicon Valley’s best investors, including Threshold, Khosla, and Y Combinator, and offer competitive salaries, comprehensive benefits, and meaningful early stage equity.

About the role:

We are looking for a Senior Product Manager to lead a new product line end to end, owning the vision, strategy, and roadmap that will guide its growth. You will define requirements, run discovery, and partner with engineering to prioritize and ship improvements. You will also own the post-sale relationship for several strategic accounts (biopharma customers, R&D organizations), the primary users of this new product line, serving as an integral link so the voice of the customer stays prevalent across our products, and drives the product development strategy

What you will do:

Lead a new product line end to end, owning the vision, strategy, and roadmap that will guide its growth

Define product requirements and write specs, partnering closely with engineering to scope, prioritize, and ship improvements

Run product discovery, including customer interviews, competitive research, and market analysis, to inform roadmap decisions

Define success metrics for the product and track performance post launch, iterating based on data

Ideate, prepare and deliver polished, data-driven insights and presentations that turn raw data into clear, compelling narratives

Own the full post-sale relationship for key biopharma and R&D accounts, serving as the primary point of contact so the voice of the customer is prevalent across all our products

Build lightweight AI-assisted tools and automations to streamline workflows and reduce manual effort over time

Collaborate with leadership on product strategy, account strategy, renewal planning, and expansion opportunities across the biopharma, R&D and insurance portfolio

Who you are:

We are looking for a few specific things that will help you succeed in this role:

5+ years of experience in product management or data science role combining strategy and execution, ideally in a biopharma or healthtech environment

Track record of owning a product roadmap end to end, from discovery through shipping and measuring impact

Strong data fluency, comfortable working in spreadsheets and SQL or Python to pull, clean, and package insights without heavy analytical support. Previous experience as a data scientist or data analyst preferred.

Excellent written and verbal communication skills, with a track record of producing polished decks, dashboards, and insight summaries

Excellent organization skills, with an ability to manage complex projects across various cross-functional stakeholders

AI native, you use AI tools as a core part of your workflow and are comfortable vibe coding lightweight solutions without engineering support

Experience translating customer or stakeholder feedback into product requirements and working alongside engineering to deliver improvements

Demonstrated ability to manage senior stakeholder relationships at large organizations, including handling escalations when needed

A hustler and a self-starter; you don’t just solve problems that others flag to you, you independently identify problems and risks before they happen, and build those solutions proactively into your plan.

Some things that are not required, but you will learn on the job:

Familiarity with rare disease, genetics, or the biopharma drug development lifecycle

Experience with patient-facing or healthcare data platforms

Formal ownership of a customer-facing platform or tool

As with all new hires at Probably Genetic, you will also need to be:

A good person. We work with some of the most marginalized populations on the planet and empathy is key

Patient-focused and motivated to have a lasting, positive impact on humanity

Comfortable in a fast-paced, often ambiguous environment with rapid change

Action-oriented and excited to build a company from the ground up

The salary range for this role is $155,000-$210,000 annually. Actual compensation offered will depend on several factors including but not limited to: work experience, education, skill level, and/or other business and organizational needs.

What we offer at Probably Genetic:

An engaging and supportive team all on a mission to improve lives

Fair and equitable compensation with competitive early-stage equity grants

Generous Flexible Time off policy, that we actually use

Parental Leave Benefits (12 weeks for both birthing and non-birthing)

Hybrid, flexible work with high-trust and autonomy

A bright, inviting, pet-friendly office in Downtown SF near transit

Company-sponsored team lunch every Thursday

A “work from anywhere” policy, up to 4 weeks a year

Regular team retreats in exciting destinations

Health Benefits including medical, dental, vision, therapy, FSA, and 401k

And so much more!

Probably Genetic is committed to fostering a welcoming and inclusive work environment for people of all genders, sexuality, ethnicity, socioeconomic background and life experiences. We urge candidates of all backgrounds to apply. If you require specific accommodations as you interview or consider working with us, please let us know.

Original posting on Probably Genetic's site ↗

Listed on hirly, a job board. hirly is not the employer: Probably Genetic is hiring for this role.

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