Senior Systems Administrator

About the role

Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who are passionate about delivering the possible to patients, and who lead with the desire to work on novel ideas. As a Sr. Systems Administrator, you will report to the Director, IT Infrastructure and help design, implement, operate, secure, and continuously improve the infrastructure services that support Sana’s corporate, research, laboratory, and regulated environments. You will serve as a senior hands-on technical resource, lead complex infrastructure initiatives, and partner with IT, Quality, Security, business stakeholders, vendors, and service providers to deliver reliable, scalable, and compliant solutions across a multi-site environment.

What you’ll do

Administer, maintain, and improve on-premises and cloud infrastructure, including Windows Server, virtualization, storage, backup and recovery, identity, directory, and core network services

Lead the technical design and implementation of infrastructure projects, upgrades, migrations, lifecycle replacements, and new site or system deployments

Operate infrastructure supporting GxP and other regulated business processes in accordance with approved procedures, change control, security, data integrity, and validation requirements

Monitor system health, capacity, performance, availability, and security; plan and execute patching, preventative maintenance, vulnerability remediation, and lifecycle activities before risks affect business operations

Troubleshoot and resolve complex incidents and recurring problems across servers, cloud services, identity platforms, storage, backup, and integrated infrastructure technologies; participate in incident response and scheduled maintenance as needed

Develop and maintain automation for routine administration, monitoring, reporting, configuration, and remediation activities

Manage backup and recovery operations, perform restore testing, and contribute to disaster recovery and business continuity planning and exercises

Create and maintain accurate architecture diagrams, configurations, procedures, standards, inventories, and as-built documentation that support consistent infrastructure engineering and operations

Provide technical leadership and peer guidance, share knowledge, evaluate emerging technologies, and recommend practical service improvements aligned with business priorities

Partner with Information Security, Quality, application teams, laboratory and manufacturing stakeholders, and other technology groups to translate business and compliance needs into supportable solutions

Coordinate with vendors and managed service providers; define technical requirements, review deliverables, and ensure services meet operational, security, and compliance expectations

Perform regulatory responsibilities in accordance with applicable Good Clinical Practices, Good Laboratory Practices, and Good Manufacturing Practices

What we’re looking for

Bachelor’s degree in computer science, information systems, engineering, or a related technical discipline and 8+ years of relevant experience, or an equivalent combination of education and work experience

Deep hands-on experience administering and troubleshooting enterprise infrastructure, including Windows Server, Active Directory, Group Policy, DNS, DHCP, virtualization, storage, backup and recovery, and monitoring platforms

Experience designing, administering, and supporting cloud and SaaS infrastructure, such as Microsoft Azure, AWS, Microsoft 365, and identity and access management services

Experience leading complex infrastructure implementations, upgrades, migrations, and lifecycle initiatives from requirements and design through deployment, documentation, and operational handoff

Demonstrated ability to analyze significant and unique technical issues, evaluate risk and tradeoffs, exercise independent judgment, and deliver effective solutions

Experience supporting infrastructure in a regulated life sciences, biotechnology, pharmaceutical, healthcare, or similarly controlled environment, with working knowledge of GxP, computer system validation, change control, data integrity, disaster recovery, high availability, and documentation practices

Ability to automate administrative and operational tasks using scripting or configuration tools such as PowerShell

Strong written and verbal communication skills, including the ability to explain technical concepts to technical and non-technical audiences and produce clear technical documentation

Ability to manage competing priorities, coordinate work across teams, and drive complex assignments to completion in a collaborative, fast-paced environment

What will separate you from the crowd

Experience administering, securing, patching, and troubleshooting Linux server environments

Experience with infrastructure qualification, validation documentation, 21 CFR Part 11, SOX, HIPAA, or other applicable regulatory and compliance requirements

Experience improving infrastructure through infrastructure as code, configuration management, orchestration, monitoring, or automated vulnerability remediation

Experience supporting multi-site research, laboratory, manufacturing, or clinical operations and delivering new or substantially modernized infrastructure environments

Relevant technical certifications in Microsoft, AWS, VMware, identity, security, networking, or IT service management

What you should know

This role may require occasional work outside standard business hours for planned maintenance, critical incidents, and project activities

Occasional travel to Sana sites or partner locations may be required

This role may require working in laboratory, manufacturing, office, and data center environments, including the ability to lift and carry equipment weighing up to 50 pounds with or without reasonable accommodation

The base pay range for this position at commencement of employment is expected to be between $180,000 and $220,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience

How we work together for patients

Lead from every seat – we seek to understand, act with honesty, and engage in the crucial conversations

Thrive as a team – we hire amazing people, are intensely curious, and cultivate inclusion and personal connectivity

Make it happen – we value vigorous debate, alignment around our decisions, and resilient execution

Get to know us

At Sana, we believe that a workforce with varied backgrounds strengthens us as a company and helps us to achieve our mission to meaningfully change the outcome of many human diseases. This belief is a pillar of our business and is critical to our success. Our goal is that Sana is the place for talented people to bring their authentic selves to work, to have a great career and to deeply, positively impact patients.

Core to our values, we believe there is nothing more important than the health and wellness of you and your family. For benefit eligible employees, we cover a generous portion of the cost for employee health coverage, making high-quality care more accessible and affordable. We offer ample time-off (various paid time off benefits, such as holidays, vacation, sick time, and parental leave), short- and long-term disability, employer paid basic life insurance, additional voluntary life insurance protection, financial wellness programs including financial planning resources, a 401(k) Plan with an immediately vested employer match, Tuition Reimbursement and Student Loan Repayment, Employee Stock Purchase Plan, commuter subsidy and a variety of wellness offerings to support each person individually. For more details on our benefits, visit Sana’s Benefits Portal .

We are committed to providing a workplace