Sr. Director, Clinical Research Operations

About N-Power Medicine

N-Power Medicine aims to establish a new paradigm in drug development by reinventing the ‘how’ and transforming clinical trials through better integration with clinical practice, ensuring broader participation by physicians and patients. We are building an exceptional multi-disciplinary team with diverse expertise spanning healthcare, engineering, technology, and regulatory, and with people who share our core value of Empowering Community through generosity, curiosity, and humility. We are working with urgency to bring better therapies to patients faster.

Position Overview

The Senior Director, Clinical Research Operations is responsible for scaling and leading the operating model that allows N-Power to run clinical research efficiently across a growing network of oncology practices. This newly created role will be accountable for the clinical research staff organization embedded at network practices and the clinical operations function responsible for study start-up, regulatory, and trial conduct.

The Senior Director will set the organizational design, operating model, and performance standards that drive scalability, staffing, capacity planning, and training infrastructure.

This is a remote role.

Role Objectives and Responsibilities

Operating Model, Performance Management and Research Operations Scale-up

Responsible for executing a long-term operating model for clinical research across the N-Power network, anticipating the organizational, process, and resourcing needs of a rapidly expanding network

Develop a scalable site activation and research integration approach that allows new practices to be brought onto the network quickly, consistently, and cost-effectively

Identify standardization, centralization, and technology enablement to reduce per-site operational burden and improve productivity.

Own the performance and reporting framework that gives executive leadership clear visibility into network research performance, risks, and investment needs.

Organizational Leadership & Execution

Build and lead a multi-layer organization spanning the distributed clinical research field team and clinical operations

Design the organizational structure, roles, career paths, and management cadence needed to sustain quality and engagement as the team scales across geographies

Establish the training, onboarding, and development infrastructure that allows the function to grow while maintaining consistent standards of practice

Build a culture of accountability, continuous improvement, and mission alignment, ensuring onsite teams are equipped to represent N-Power's value proposition to practices and physicians

Drive improvements in operational efficiency and unit economics as the network grows

Serve as an escalation point for site-level relationship risks and support rollout of new initiatives or workflow changes across the network

Partner closely with Network Operations leadership and other cross-functional teams to align CRS and Clinical Operations priorities with broader network strategy

Perform additional duties and responsibilities as required.

Education, Experience, Behavioral Competencies, & Skills

10+ years of experience in clinical research operations, including direct, hands-on oncology clinical trial experience

Proven success leading and managing a multi-layer, distributed, research workforce at scale

Strong understanding of oncology practice workflows, including academic/community research and practice administration

Demonstrated ability to build repeatable playbooks, SOPs, and processes as teams and programs grow

Track record of driving operational efficiency through process standardization, centralization, and technology adoption

Experience building staffing models, capacity plans, and KPI/reporting frameworks

Experience designing training and development infrastructure for a distributed clinical workforce

Bachelor’s degree or equivalent professional experience

Exceptional written and verbal communication skills, with the ability to engage and influence senior stakeholders, clinical teams, and technical experts alike

Collaborative, hands-on leader who thrives in dynamic environments; generous, curious, and humble

Preferred

Familiarity with CTMS, EDC, or similar clinical trial systems as they relate to site-level workflow

Travel Requirements

Travel expected on an as-needed basis to support regional teams. Up to 25%

Pay Information

The expected salary range for this position is $215K-230K. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. N-Power Medicine (NPM) offers equity at hire as well as a discretionary annual bonus which may be available based on Company performance. This position is eligible for company benefits.

More About Us

We are a mission-driven, well-funded, rapidly growing company, eager to attract passionate professionals offering a highly attractive compensation package with a balanced and flexible work environment, competitive industry benefits as well as a 401K plan.

We are an Equal Opportunity Employer and value diversity at our company. We do not discriminate based upon race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.

Applicants must be currently authorized to work in the U.S. on a full-time basis. The Company will not sponsor applicants for work visas.

Please note that state-specific background checks and screenings may be required for this role. Employment is contingent upon successfully passing all applicable screenings.

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