Staff Software Engineer, Neuronavigation and Autonomy

Title: Staff Software Engineer, Neuronavigation and Autonomy

Functional Area: Software Engineering

Department: R&D

Reports to: Sr. Director, Image Processing Algorithms

Location: Burlingame, CA (onsite)

Company background

Magnus Medical, Inc. (“Magnus”) is an innovative company that has developed and commercialized a SaaS-based offering to provide a FDA-cleared, personalized and targeted treatment of patients with Treatment Resistant Depression. Magnus is also developing similar solutions for other mental health conditions including but not limited to bipolar disorder, postpartum depression, and anxiety.

We are a venture-funded therapeutic medical devices company, led by industry veterans, with the mission of freeing individuals from the symptoms of depression and other neuropsychiatric diseases using personalized and accelerated neuromodulation technology. Our efforts are grounded in science, informed by clinical data, and inspired by the strength of those who live with psychiatric disease. We offer the ability to make the world a better place, in collaboration with like-minded colleagues who value communication, integrity, and cooperation. We are looking for individuals who are personally and boldly committed to improving treatment for mental health.

Role Description

The product is composed of Magnus Cloud and Magnus Neuromodulation software. The cloud analyzes fMRI to identify a personalized target within the brain linked to patients’ emotional state. This target is then passed on to the neuromodulation software which guides clinicians through treatment using SAINT.

• We are extending the neuromodulation software with real-time neuronavigation and autonomous treatment delivery: a system that tracks the patient’s head live, localizes the treatment coil in the patient’s own imaging space, and drives a robotic arm to place and hold the coil on target through a session. The concept is proven and the production implementation is well under way. As a Staff Software Engineer you will be its technical owner, working at the intersection of computer vision, real-time systems, and robotics, and accountable for it through to release.
• The scope runs from live tracking and coil localization through robotic integration, automated coil placement, automated motor threshold determination, and the safety architecture that makes autonomous operation acceptable. You will also own the bench testing that proves clinical accuracy under FDA design controls. We expect real depth in one of these areas, systems-level thinking across the rest, and the judgment to know when a result is solid enough to guide the treatment of a patient. This is a senior individual contributor role, based onsite in Burlingame, CA.

Essential Responsibilities

Own the real-time neuro-navigation and autonomy stack end to end: architecture, algorithms, performance, and correctness

Develop, optimize, and validate live head tracking and coil localization, treating accuracy, robustness, and latency as one problem: computer vision, registration, sensor fusion, and filtering against system-level accuracy requirements

Design and optimize the C++ runtime connecting live sensor and robot data to CV and ML inference: low-latency data flow, concurrency, and GPU acceleration within a fixed latency budget

Own integration with the robotic arm: real-time control interfaces, hand-eye and tool-tip calibration, coordinate frames across imaging, tracking, robot, and patient, and motion constraints for work near a patient

Build the closed-loop autonomy that delivers treatment: automated coil placement on target and continuous motion compensation and drift correction through a session

Develop automated motor threshold determination: closed-loop control of stimulation intensity, detection of the motor response, and adaptive threshold estimation

Design the safety architecture for a system operating autonomously on a patient: interlocks, workspace and force limits, clinician override, and defined behavior on tracking loss or other degraded conditions

Apply machine learning to perception where it outperforms classical methods: semantic segmentation, landmark detection, and instrument detection, validated to clinical standards

Own sensor integration across cameras, depth sensors, and optical trackers: calibration, time synchronization, and error characterization

Own the accuracy and robustness test strategy and prove the system meets it: bench, phantom, and system-level accuracy testing with the fixtures and ground truth it depends on; identify failure modes; author the protocols and reports supporting design verification and FDA submissions

Own the medical device software lifecycle for these components: requirement definition, risk assessment, design documentation, and release

Own the interfaces to the upstream imaging pipeline that supplies anatomical models and targets, and to the clinical software that presents guidance

Set technical direction, mentor engineers, and work across clinical, scientific, quality, and regulatory teams

Work onsite in Burlingame, CA, with regular hands-on time on sensors, robot, and bench test fixtures

Required Skills and Qualifications

MSc. degree in computer science, engineering, physics, applied mathematics, or a related technical field, or equivalent practical experience

Expert-level modern C++ with 6+ years delivering production real-time systems: multi-threaded and concurrent design, deterministic low-latency execution, memory and cache-aware optimization, and profiling under hard timing constraints

Proficiency in Python for algorithm prototyping, data analysis, and tooling

Depth in at least one of the following, with the appetite to build competence in the others: geometric computer vision and 3D perception; numerical methods for spatial estimation and sensor fusion; robotics, including kinematics and real-time control; machine learning for perception

Working knowledge of camera calibration, registration, multi-view geometry, rigid-body transforms, and coordinate-frame reasoning

Experience building deterministic data flow over asynchronous sensor streams on Linux, including buffering strategies and time synchronization across devices

Experience with closed-loop or autonomous systems, including state machines, degraded modes, and safety-aware design

A measurement-driven approach to accuracy and robustness, including designing and running the bench tests that prove a system meets its requirements

Demonstrated ownership of a complex subsystem from algorithm through released product, including evolving a substantial codebase you did not write

Systems-level thinking, with the ability to set technical direction independently and work across engineering, clinical, quality, and regulatory teams

Preferred Qualifications

Software development in a regulated medical device environment: IEC 62304, ISO 14971, design controls, and documentation that has supported an FDA submission or audit

Familiarity, knowledge and/or experience with 21 CFR 820, Quality Management System Regulation, preferred/desired

Surgical navigation, robotic surgery, or another image-guided or safety-critical autonomous system, including patient-to-image registration

Robot integration: hand-eye calibration, forward and inverse kinematics, impedance or force control, vendor real-time control APIs or ROS, and functional safety

Cameras and depth sensors (stereo, structured light, time-of-flight), including vendor SDKs and driver-level integration

Closed-loop physiological control or biosignal processing, such as EMG, evoked potentials, or adaptive stimulation

GPU-accelerated computing such as CUDA, and ML inference frameworks such as TensorRT or ONNX Runtime

Familiarity with MRI-based anatomical models and coordinate spaces, and with TMS or neuromodulation

Salary Range: $170,000 - $220,000

The annual base salary range for this