PostDoc in Drug Discovery / Neutrophil-driven Inflammation (m/w/d)

Scope of duties

• As a PostDoc in the research group of Prof. Christoph Klein, you will join a translational research program with the option to take on a leadership role.
• You will be involved in a first-in-class drug discovery project aimed at selectively modulating neutrophil-driven inflammation. Your work will cover the differentiation and functional characterization of iPSC-derived neutrophils, the establishment and execution of biochemical and cellular screening assays, as well as multi-omics profiling (transcriptomics, proteomics, metabolomics) in collaboration with our academic and industrial partners.
• You will help plan and coordinate ongoing experiments, prepare scientific data for publication and grant applications, and support the scientific supervision of junior researchers.

Our requirements

· Completed PhD in Biology, Biochemistry, Biotechnology, Pharmacology or a comparable field

• · Solid experience in the following areas:
• · Molecular biology and cell biology techniques
• · iPSC cultivation and/or differentiation into immune cell types
• · Establishment and execution of biochemical, cellular or high-throughput screening assays
• · Experience with in vitro or in vivo functional assays and multi-omics data analysis is an advantage
• · The ability to work independently, as well as in an interdisciplinary and international team
• · A structured, meticulous and solution-oriented working style
• · Excellent English skills; German skills are an advantage

Our offer

· The position is initially funded for two years . Subject to a positive scientific re-evaluation, an extension is possible

• · An innovative and challenging position within the research group of Prof. Christoph Klein, operating at the interface of translational immunotherapy, stem cell biology and precision medicine.
• · An international and interdisciplinary research environment, supported by close collaboration with academic and industrial partners within an established research network
• · Close collaboration with basic scientists, bioinformaticians and clinician scientists on two complementary translational projects
• · A collaborative, supportive and inspiring working environment that encourages scientific independence
• · Employment according to the German public-sector collective agreement (TV-L), including annual leave and additional benefits in accordance with the applicable regulations