Sr. Director, Sales Training

Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.

Our lead product candidate, lysergide tartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.

Guided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.

Together we are moving psychiatry forward—beyond better, into a boundless future. Join us!

This is a high-impact, foundational leadership role reporting to the VP of Sales. You will own the end-to-end strategy and execution of sales training and capability development for a novel CNS product that will require deep scientific fluency, nuanced patient and HCP engagement, and rigorous compliance. You will shape how our future sales organization and adjacent commercial field teams master the science, the patient journey, competitive differentiation, and the unique considerations of bringing a novel psychedelic therapy to market. Success in this role will directly influence launch readiness, field force excellence, and long-term commercial performance.

Location: Fully remote within the U.S., with frequent travel required. A significant portion of training delivery and team collaboration will occur at our Philadelphia office; therefore, candidates based in or near the Philadelphia area are strongly preferred.

Responsibilities:

Design and lead a comprehensive sales training curriculum covering product knowledge, clinical data, disease-state education (GAD, MDD), competitive landscape, objection handling, account management, and compliant promotional practices

Build training programs tailored to the unique aspects of DT120 ODT, including administration considerations, clinical observation, patient selection, and the evolving regulatory and market access environment

Partner closely with Commercial Leadership, Medical Affairs, Market Access, Compliance, and Legal to ensure training content is scientifically accurate, strategically aligned, and fully compliant

Develop and deliver high-impact live, virtual, and digital training experiences for new-hire onboarding, ongoing skill development, launch readiness, and continuous learning— with substantial in-person delivery expected at the Philadelphia office and other locations as needed

Lead the sales training function, leveraging external partners and vendors as needed to deliver high-quality programs; establish best-in-class processes, tools, and metrics for training effectiveness and field capability

Create measurement frameworks to assess knowledge retention, behavioral change, and business impact; use data and field feedback to continuously refine programs

Support sales leadership in coaching frameworks, performance management, and the development of sales managers as trainers and coaches.

Drive a culture of excellence, curiosity, and patient-centricity across the commercial organization

Contribute to broader commercial readiness planning and serve as a key voice on field capability needs

Qualifications:

Bachelor’s degree required; advanced degree (MBA, life sciences, education, or related) preferred

Minimum 12 years of progressive experience in the pharmaceutical/biotech industry within the commercial function, including but not limited to; sales training, sales excellence, and or commercial capability development

Experience in leading successful sales training initiatives, product launch initiatives, leadership development, curriculum design and training evaluation

Proven track record building or scaling training functions in specialty, CNS, psychiatry, or complex therapeutic areas required; experience with novel modalities, launch products, or highly regulated spaces is highly valued

Deep understanding of adult learning principles, instructional design, and modern training delivery methods (live, virtual, e-learning, simulations, role-play, etc.)

Experience in managing consultants and vendor relationships to ensure effective design and implementation of training solutions

Strong scientific acumen and ability to translate complex clinical data into compelling, compliant field narratives

Experience collaborating across Commercial, Medical, Access, and Compliance functions in a matrixed biotech or pharmaceutical environment

Exceptional communication, facilitation, and stakeholder-management skills; ability to influence senior leaders and inspire field teams

Demonstrated success recruiting, developing, and leading high-performing teams

High integrity, intellectual curiosity, and a genuine passion for advancing mental health care

Comfortable with frequent travel and a hybrid delivery model that includes regular time in the Philadelphia office

Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.

Employees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including:

100% paid health benefits including Medical, Dental and Vision for you and your dependents

401(k) program with company match and vesting after the turn of the first month after your start date

Flexible time off

Generous parental leave and some fun fringe perks!

The starting base pay range for this position:

$250,000 — $280,000 USD