Sr. Director, Strategic Portfolio Management Lead

Why Pfizer

A career at Pfizer offers opportunity, ownership and impact. All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success, contribute to an ownership culture that values diverse perspectives, and impact the health and lives of millions of people. Pfizer seeks talent inspired by our purpose: breakthroughs that change patients’ lives.

Role Summary

Serve as the strategic front door and portfolio-orchestration capability for Platform & Enablement Services, connecting enterprise demand to the right capabilities and providing integrated visibility across priorities, resources, investments and dependencies.

What You Will Achieve

Clear, consistent front door for significant demand

Integrated leadership visibility across priorities, investments, resources, milestones and dependencies

Higher-quality investment and resource decisions

Disciplined intake, prioritization and portfolio decision-making

Effective handoffs from demand through execution and ongoing ownership

Earlier shaping of complex strategic demand, including business development and mergers and acquisitions

How You Will Achieve It

You will serve as a primary entry point into Platform & Enablement Services for significant enterprise and Global Business Services demand.

You will assess incoming needs for strategic fit, urgency, scale and required capabilities and translate demand into preliminary delivery and resource requirements.

You will establish portfolio governance, structure and controls and coordinate assessment of requirements, dependencies and sequencing across capabilities.

You will maintain integrated visibility of demand, committed work, roadmaps, capacity, investments, risks and cross-portfolio dependencies.

You will integrate value, urgency, capacity, AI-enablement opportunities and dependencies into recommendations to proceed, sequence, defer, redirect or further assess demand.

You will partner with sponsors and Finance to shape and challenge business cases, investments and resource assumptions.

You will advise leaders on complex enterprise initiatives, including business development, mergers and acquisitions and other strategic demand, before work moves into execution.

Decision Rights and Role Boundaries

The role decides intake and assessment approaches, portfolio-governance routines, visibility standards and coordination requirements. It recommends or co-decides portfolio priorities, sequencing, investment and capacity trade-offs and the appropriate pathway for significant demand. It does not own business outcomes, functional process decisions, solution development or delivery execution; accountability transitions to the appropriate delivery capability once demand is mobilized, while this role retains portfolio-level governance, visibility and coordination.

Basic Qualifications

Bachelor’s degree in Business, Finance, Strategy, Operations, Engineering, Information Systems or a related field.

Successful candidates typically have at least 12 years of progressive experience in enterprise portfolio management, demand management, strategic planning or transformation governance, ideally in Global Business Services.

Typically at least 7 years of experience leading enterprise portfolio strategy, demand shaping, portfolio governance, capacity planning and investment recommendations.

Typically at least 5 years of experience developing or challenging business cases, resource strategies and investment recommendations for complex enterprise initiatives.

Demonstrated executive communication, systems thinking and influence without direct ownership of delivery or business outcomes.

Preferred Qualifications

MBA or master’s degree in Business, Strategy or Operations.

PfMP, PMP, finance or change-management certification.

Pharmaceutical or life-sciences experience.

Experience establishing portfolio governance in Global Business Services or shared services.

M&A, integration or major strategic-initiative experience and development of capacity models used for leadership decisions.

Key Relationships

GBS leaders, functional owners and business stakeholders.

Finance and investment partners.

Digital & Technology.

Business Development and M&A stakeholders.

Transformation Delivery, Data & Analytics, Innovation & AI, and Process & Platform teams.

Capabilities and Leadership Expectations

Enterprise portfolio management.

Strategic intake and demand shaping.

Portfolio governance and visibility.

Capacity and investment recommendations.

M&A and strategic-demand coordination.

Executive advisory and systems thinking.

Other Job Details:

• •Last day to Apply: November 6th, 2026
• •Work Location Assignment: Hybrid

The annual base salary for this position ranges from $214,900.00 to $358,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided applies to the Tampa, FL location only. The salary range provided does not apply to any other United States location or locations outside of the United States.


This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.



Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing